136 2 BasicPrinciplesofImmunology
Table2. 13 Continued:ImportantCDAntigens
Designation
(alternatives)
Cellswhichexpressthe
antigen
Functions
CD2 1 (CR2) MatureBcells,follicular
dendriticcells
Receptorforthecomplement
components(CR)C3dandthe
Epstein-Barrvirus.Formsa
co-receptorforBcellstogether
withCD1 9 andCD8 1
CD22 MatureBcells AdhesionofBcellstomonocytes
andTcells
CD23(FceRII) MatureBcells,activated
macrophages,eosinophils,
folliculardendriticcells,
bloodplatelets
Low-affinityreceptorforIgE,and
ligandfortheCD19:CD21:CD8 1
coreceptor
CD25(Tac) ActivatedTcells,Bcells,
andmonocytes
achainoftheIL-2receptor,
associatedwithCD1 22 andthe
IL-2Rcchain
CD26 ActivatedBandTcells,
macrophages
Aproteasewhichmaybe
involvedinHIVentryintohost
cells
CD28 SubgroupofTcells,activated
Bcells
Activationofnaı ̈veTcells.
Areceptorforcostimulatory
signal(signal2);bindsCD80
(B7.1)andB7.2
CD29 Leukocytes b 1 subunitofc 1 integrins,asso-
ciatedwithCD49ainVLA-1
integrin
CD34 Hematopoieticprecursorcells,
capillaryendothelium
LigandforCD62L(L-selectin)
CD35(CR1) Erythrocytes,Bcells,mono-
cytes,neutrophilsandeosino-
phils,folliculardendriticcells
Complementreceptor1;binds
C3bandC4b.Alsomediates
phagocytosis
CD38 EarlyBandTcells,activated
Tcells,germinalcenterBcells,
plasmacells
B-cellproliferation?
CD39 ActivatedBcells,activated
naturalkillercells,macro-
phages,dendriticcells
Unknownfuction,butmay
mediateadhesionofBcells
2
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Kayser, Medical Microbiology © 2005 Thieme
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