Medical Microbiology

(ff) #1
136 2 BasicPrinciplesofImmunology

Table2. 13 Continued:ImportantCDAntigens

Designation
(alternatives)

Cellswhichexpressthe
antigen

Functions

CD2 1 (CR2) MatureBcells,follicular
dendriticcells

Receptorforthecomplement
components(CR)C3dandthe
Epstein-Barrvirus.Formsa
co-receptorforBcellstogether
withCD1 9 andCD8 1
CD22 MatureBcells AdhesionofBcellstomonocytes
andTcells
CD23(FceRII) MatureBcells,activated
macrophages,eosinophils,
folliculardendriticcells,
bloodplatelets

Low-affinityreceptorforIgE,and
ligandfortheCD19:CD21:CD8 1
coreceptor

CD25(Tac) ActivatedTcells,Bcells,
andmonocytes

achainoftheIL-2receptor,
associatedwithCD1 22 andthe
IL-2Rcchain
CD26 ActivatedBandTcells,
macrophages

Aproteasewhichmaybe
involvedinHIVentryintohost
cells
CD28 SubgroupofTcells,activated
Bcells

Activationofnaı ̈veTcells.
Areceptorforcostimulatory
signal(signal2);bindsCD80
(B7.1)andB7.2
CD29 Leukocytes b 1 subunitofc 1 integrins,asso-
ciatedwithCD49ainVLA-1
integrin
CD34 Hematopoieticprecursorcells,
capillaryendothelium

LigandforCD62L(L-selectin)

CD35(CR1) Erythrocytes,Bcells,mono-
cytes,neutrophilsandeosino-
phils,folliculardendriticcells

Complementreceptor1;binds
C3bandC4b.Alsomediates
phagocytosis
CD38 EarlyBandTcells,activated
Tcells,germinalcenterBcells,
plasmacells

B-cellproliferation?

CD39 ActivatedBcells,activated
naturalkillercells,macro-
phages,dendriticcells

Unknownfuction,butmay
mediateadhesionofBcells

2


All rights reserved. Usage subject to terms and conditions of license

Kayser, Medical Microbiology © 2005 Thieme
All rights reserved. Usage subject to terms and conditions of license.
Free download pdf