Vertebrate Development Maternal to Zygotic Control (Advances in Experimental Medicine and Biology)

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546


Posterior marginal zone (PMZ), 212, 223, 226,
241–243, 316–318, 327, 336–338,
340, 350, 353
Postplasm, 412
Posttranscriptional regulation, 392, 393
PP1-interacting proteins (PIPs), 98
Aurora-B, 98
in regulating, cell cycle, 99–100
regulating PP1 activity, 99
Repo-Man targets, 98
RVxF’ motif, 98
SILK and MyPhone motifs, 98
substrates and regulators, 98
PP2A-B55 phosphatase
AGC-type kinase Gwl, 94
and Ensa/Arpp19, 95–96
Cdk1/cyclin-B, 92, 93
inhibitors Ensa/Arpp19, 94–95
invertebrates and vertebrates, 92
reactivation, 95
regulation, 92–93
siRNA-mediated knockdown, 92
PP2A-B ́56 phosphatase
activity of Cdc25, 96, 97
and APC/C, 97
chromosome segregation, 96
DNA damage, 96
DNA damage-responsive checkpoint, 96
in mitosis, 96
phosphorylation, 96
Presumptive primordial germ cell (pPGC).,
386, 404
Primitive streak, 273
Primordial germ cells (PGCs), 404
Blimp1, 4
cell signaling systems, 407
chicken embryo, 4
germline, 4
migration, 393, 395
mouse, 4
nanos/Pumilio, 408
post-transcriptional regulation, 392, 393
preformation, 3
Protamine/histone exchange, 518
Protein degradation
autophagy-mediated lysosomal
degradation, 510–511
ubiquitin-proteasome pathway, 510–514
Protein kinase A (PKA), 95, 96, 99, 104
Protein phosphatases (PPs), 91–97
PP1, 98–100
PP2As (see Type 2A protein phosphatases
(PP2As))


Proteome analysis, OET
catalogue of Xenopus oocytes, 513
clusters of proteins, 513
2D electrophoresis, 512, 513
fully grown and MII oocytes, 513
iTRAQ analysis, 513
maternal protein degradation, 514
maternal proteins, 514
meiotic maturation, 513
oocytes and early embryos, 513
protein detection and quantification, 514
protein-degrading mechanisms, 514
single-cell proteomic analysis of Xenopus
eggs, 513
Xenopus oocyte, 513

R
Really interesting new gene (RING) finger
protein Apc11, 89
Regulated translation
BMP signaling pathway, 63–65
CPE/CPEB-dependent polyadenylation
and translation, 59
FGFR signaling pathway, 62
mRNA polyadenylation, 58
Xenopus maternal mRNAs, 58
Reprogramming, 494, 515–517, 519
Retinoic acid (RA) signaling pathway, 182
Ribosomal RNA (rRNA), maternal, 508–509
RNA interference (RNAi), 504
molecular mechanisms, 496
siRNAs, 498–499
RNA localization, 186–189, 194, 195
animal pole
cycB localization, 195
oogenesis, 194
RNA-binding proteins, 195
zebrafish, 194
and AV axis, 178–179
AV polarity, 185
Bb
CAC motifs, 187
late pathway, 188, 189
nanos MCLE motif, 187
oogenesis, 186
photobleaching, 188
Rbpms2, 187
themes, 186
UGCAC, 187
Xenopus and zebrafish, 186
METRO pathway, 185
MS2 RNA-labeling system, 189

Index
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