Science - USA (2018-12-21)
PHOTO: ZACHARY HASLICK/AERIAL ASSOCIATES PHOTOGRAPHY, INC./NOAA GLERL/FLICKR 1370 21 DECEMBER 2018 • VOL 362 ISSUE 6421 sciencem ...
Large Newspaper (Circulation of 150,000 or more) Gold Award: Mike Hixenbaugh, The Houston Chronicle, for “Alive Inside” (series) ...
a Saturn-mass planet, trailing behind it in its orbit. They com- bined this with observations of several other exoplanets to sho ...
SCIENCE sciencemag.org PHOTO: AGAMI PHOTO AGENCY/ALAMY STOCK PHOTO advertised percentage of area protected. However, recent rese ...
RESEARCH | IN OTHER JOURNALS sciencemag.org SCIENCE IMMUNOLOGY Lymph node mass transport Cytokines are transported around the bo ...
sciencemag.org SCIENCE RESEARCH CELL BIOLOGY Protecting the heart Excitation-contraction (E-C) coupling is fundamental to heart ...
SCIENCE sciencemag.org of the polyunsaturated fatty acid 5-oxoETE was selectively increased in colonic biopsies from patients wi ...
RESEARCH ARTICLE SUMMARY ◥ CELL BIOLOGY E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription r ...
RESEARCH ARTICLE ◥ CELL BIOLOGY E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator ...
and nuclear accumulation of JP2NT. Consistent with this notion, we found that both isoprotere- nol infusion (Fig. 1D and figs. S ...
JP2NT translocation, we adapted an inducible split tobacco etch virus protease (sTEVp) system (Fig. 1G, i) ( 35 ). A TEVp substr ...
nuclear localization signal (NLS) at positions 488 to 492 (Lys-Arg-Pro-Arg-Pro) and a bipartite NLS-like peptide (bNLS) at posit ...
MORN domains from JP2NT (JP2NTDMORNs)did not influence its distribution in the nucleus or its association with chromatin (Fig. 2 ...
compared JP2NT occupancy of genomic loci with that of cardiac polymerase II (Pol II) and acetylated histone H3 Lys^9 (H3K9ac, a ...
(fig. S6B). Biotinylated oligo DNA pull-down assayconfirmedthattheJP2NTtransgeneas well as endogenous full-length JP2 from heart ...
larger myocardium mass (Fig. 6F), higher end diastolic volume (EDV) (Fig. 6H) and end systolic volume (ESV) (Fig. 6I), and lower ...
that connect T-tubules and the SR membrane ( 8 ). Here, we discovered that JP2 contains additional regulatory domains that exten ...
RESEARCH ARTICLE SUMMARY ◥ STRUCTURAL BIOLOGY Structure of human TFIID and mechanism of TBP loading onto promoter DNA Avinash B. ...
RESEARCH ARTICLE ◥ STRUCTURAL BIOLOGY Structure of human TFIID and mechanism of TBP loading onto promoter DNA Avinash B. Patel1, ...
in vitro studies showing that the HFDs of TAF11-TAF13 constitute the bridge between TBP and the rest of TFIID ( 15 ). Altogether ...
«
1
2
3
4
5
6
7
8
9
»
Free download pdf