Nature - 15.08.2019
Letter reSeArCH Extended Data Fig. 2 | The effects of cell lysates, ATP and heat treatment of CaM on the activity of SidJ and it ...
reSeArCH Letter Extended Data Fig. 3 | The IQ motif of SidJ is required for its optimal response to CaM. a, b, The IQ motif is r ...
Letter reSeArCH Extended Data Fig. 4 | SidJ forms a stable heterodimer with CaM at a molar ratio of 1:1. a, SidJ(∆N99) maintains ...
reSeArCH Letter Extended Data Fig. 5 | Overall structure of the SidJ–CaM complex in one asymmetric unit and the comparison of co ...
Letter reSeArCH Extended Data Fig. 6 | Interactions between CaM and Ca^2 + from the crystal structures and the role of Ca^2 + in ...
reSeArCH Letter Extended Data Fig. 7 | The mechanism of SidJ-induced CaM- dependent self-AMPlyation and SdeA glutamylation. a, S ...
Letter reSeArCH Extended Data Fig. 8 | Intracellular growth phenotypes associated with the ∆sidJ mutant expressing SdeA and its ...
reSeArCH Letter Extended Data Fig. 9 | SidJ functions to regulate the activity of SdeA during L. pneumophila infection. a, SdeA( ...
Letter reSeArCH extended data table 1 | data collection and refinement statistics *For each structure one crystal was used. Valu ...
1 nature research | reporting summary October 2018 Corresponding author(s): Dr. Zhao-Qing Luo Last updated by author(s):Jul 7, 2 ...
2 nature research | reporting summary October 2018 Field-specific reporting Please select the one below that is the best fit for ...
3 nature research | reporting summary October 2018 anti-HIF-1a (R&D systems, cat#MAB1536): https://www.rndsystems.com/produc ...
Letter https://doi.org/10.1038/s41586-019-1456-0 CD24 signalling through macrophage Siglec-10 is a target for cancer immunothera ...
Letter reSeArCH were less phagocytic than unstimulated macrophages at baseline levels (Extended Data Fig. 2f). We found that sti ...
reSeArCH Letter adenocarcinoma (Panc1), pancreatic neuroendocrine tumour (APL1) and small-cell lung cancer (NCI-H82)—and no effe ...
Letter reSeArCH To investigate whether the protection against phagocytosis con- ferred by CD24 could be recapitulated in vivo, G ...
reSeArCH Letter emergence of subclones of CD24+ cells that did not have biallelic CD24 deletion (Extended Data Fig. 8d, e). TAM ...
Letter reSeArCH Methods Statistics. Sample sizes were modelled after those from existing publications regarding in vitro immune ...
reSeArCH Letter described above. EpCAM+ tumour cells were purified on an autoMACS pro separator (Miltenyi) by first depleting sa ...
Letter reSeArCH from the National Heart, Lung, and Blood Institute (1T32HL120824 to B.W.Z.). The contents of this manuscript are ...
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