Nature - 15.08.2019

Letter reSeArCH 10% dialysed FBS. Cells were traced for 6 h, and tracing was followed by cellular metabolite extraction. Metabol ...

reSeArCH Letter Liu, X., Ser, Z. & Locasale, J. W. Development and quantitative evaluation of a high-resolution metabolomic ...

Letter reSeArCH Extended Data Fig. 1 | Dietary restriction of methionine rapidly and specifically alters methionine and sulfur m ...

reSeArCH Letter Extended Data Fig. 2 | Dietary restriction of methionine alters methionine metabolism in PDX models of colorecta ...

Letter reSeArCH Extended Data Fig. 3 | Methionine restriction leads to specific cell- intrinsic metabolic alterations in tumours ...

reSeArCH Letter Extended Data Fig. 4 | Methionine restriction inhibits cell proliferation, and most substantially alters cystein ...

Letter reSeArCH Extended Data Fig. 5 | Dietary restriction of methionine sensitizes PDX models of colorectal cancer to 5-FU chem ...

reSeArCH Letter Extended Data Fig. 6 | Inhibition of cell growth mediated by methionine restriction is largely due to interrupti ...

Letter reSeArCH Extended Data Fig. 7 | Dietary restriction of methionine sensitizes mouse models of RAS-driven autochthonous sar ...

reSeArCH Letter Extended Data Fig. 8 | Dietary restriction of methionine can be achieved in humans. a, Heat map of significantly ...

Letter reSeArCH Extended Data Fig. 9 | Comparative metabolic effects of methionine restriction across mouse models and humans. a ...

reSeArCH Letter extended data table 1 | Methionine concentrations in plasma, tumour and liver across mouse models and humans Tis ...

1 nature research | reporting summary October 2018 Corresponding author(s): Jason Locasale Last updated by author(s):May 21, 201 ...

2 nature research | reporting summary October 2018 Field-specific reporting Please select the one below that is the best fit for ...

3 nature research | reporting summary October 2018 Wild animals No wild animals were involved in this study. Field-collected sam ...

Letter https://doi.org/10.1038/s41586-019-1426-6 Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalli ...

Letter reSeArCH the transcriptional activity of YAP (also known as YY1AP1) with its primary binding partners, the TEAD family of ...

reSeArCH Letter regulatory activity even at high density^20 ,^24 ,^25 (Extended Data Fig. 8a– d). HCT116 or 211H cells that expr ...

Letter reSeArCH to the promoter regions of TFRC and ACSL4 genes, and binding was enhanced by overexpression of YAP(S127A) (Fig.  ...

reSeArCH Letter cadherin–NF2–Hippo–YAP signalling axis. Considering that multi- cellular organisms are under frequent insult of ...