The_20Scientist_20March_202019 (1)

ans cope with high-altitude conditions is similar to an allele found in the Deniso- van genome, and likely was acquired many mil ...

20 THE SCIENTIST | the-scientist.com XING GAO NOTEBOOK remains have been found in a cave in northern China, suggesting that the ...

03.2019 | THE SCIENTIST 21 MODIFIED FROM © ISTOCK.COM; THE SCIENTIST STAFF I t is widely accepted that all animals and plants ho ...

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03.2019 | THE SCIENTIST 23 MODUS OPERANDI © GEORGE RETSECK T he progression of an immune response can be thoroughly studied in t ...

24 THE SCIENTIST | the-scientist.com © ISTOCK.COM, JARUN011 I t’s not clear w hy, but the Greater Mekong Subregion—Cambodia, sou ...

CREDIT LINECREDIT LINE IN THE BLOOD:Red blood cells infected with a malaria parasite (purple) circulate with uninfected RBCs (gr ...

Vaccine Initiative, a nonprofit dedicated to malaria prevention and eradication. With no viable alternative to arte- misinin, in ...

03.2019 | THE SCIENTIST 27 preserving the toxicity of this byproduct of the parasite’s digestion of hemoglobin. Nor- mally, the ...

ACT OF RESISTANCE Plasmodium falciparum resistance to artemisinin-based combination therapies ( A C Ts ) started to crop up arou ...

CREDIT LINE PARTNER DRUG RESISTANCE In red blood cells, P. falciparum digests human hemoglobin to feed itself. In addi- tion to ...

30 THE SCIENTIST | the-scientist.com until DHA-PP–resistant PLA1 parasites emerged in 2008 that things started to get bad, he sa ...

Even with ample ACT options, chang- ing up the treatments typically given in a particular area is easier said than done, says Am ...

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THE VIRAL BRAIN Scientists may need to seriously reconsider the cast-aside hypothesis that pathogens can play a part in neurodeg ...

34 THE SCIENTIST | the-scientist.com Looking into the literature, Smeyne found more hints of influ- enza’s ability to damage the ...

CROSSING BLOOD-BRAIN BARRIER When interacting with the nervous system, viral particles can cross the blood-brain barrier directl ...

36 THE SCIENTIST | the-scientist.com KORTE/HOSSEINI, DATA PUBLISHED IN HOSSEINI ET AL., JNS ,^2018 tion in the brains of infecte ...

03.2019 | THE SCIENTIST 37 erial from cell to cell, says Jason Shepherd, a neuroscientist at the University of Utah and coauthor ...

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