The_20Scientist_20March_202019 (1)

03.2019 | THE SCIENTIST 39 B efore the advent of general anes- thesia in the mid-19th century, surgery was a traumatic experi- e ...

40 THE SCIENTIST | the-scientist.com The modern definition of general anesthesia requires that five endpoints are achieved. (See ...

OSCILLATIONS IN THE ANESTHETIZED BRAIN Anesthetics’ interactions with neural receptors alter how neurons work, and as a conseque ...

42 THE SCIENTIST | the-scientist.com hypothesis. Then, Nicholas Franks and William Lieb of Imperial College London showed that t ...

03.2019 | THE SCIENTIST 43 thesia has yielded insights not only into the effects of anesthetics themselves, but also into neural ...

Looking for a new career in the life sciences? Search for a job that will spark an innovation. Visit The Scientist’s careers por ...

01.2018 | THE SCIENTIST 45 CREDIT LINE N atural killer (NK) cells, known for their ability to kill tumor cells, are promising ag ...

WEBINAR SPONSORED BY: Immune responses are controlled by an exquisite system of stimulatory and inhibitory checkpoints. Cancer c ...

84th Cold Spring Harbor Laboratory Symposium on Quantitative Biology RNA Control & Regulation May 29 - June 3, 2019 Poster A ...

THE PAPER Y. Yu et al., “Dna2 nuclease deficiency results in large and complex DNA insertions at chro- mosomal breaks,” Nature, ...

03.2019 | THE SCIENTIST 49 REPRINTED WITH PERMISSION FROM I. ROSENSHINE ET AL., SCIENCE , 245:1387 (1989); © ISTOCK.COM, JOHAN63 ...

50 THE SCIENTIST | the-scientist.com PROFILE © DECODE GENETICS K ári Stefánsson remembers exactly where he was when he formulate ...

03.2019 | THE SCIENTIST 51 KÁRI STEFÁNSSON President, CEO, and director of deCODE genetics, Reykjavik, Iceland Professor of Facu ...

52 THE SCIENTIST | the-scientist.com PROFILE there is a genetic component to the most common late-onset form of Parkinson’s dise ...

I t’s safe to say that most chemistry majors don’t envision becoming experts in dissecting mosquito throats, but that’s the posi ...

54 THE SCIENTIST | the-scientist.com LAB TOOLS MODIFIED FROM © ISTOCK.COM, TERA VECTOR Knock It Into the Park Techniques for upp ...

03.2019 | THE SCIENTIST 55 THE SCIENTIST STAFF use to find the correct dose, Chesnut says: you want to kill cells without insert ...

56 THE SCIENTIST | the-scientist.com LAB TOOLS ADAPTED FROM AN ILLUSTRATION BY GREG FINDLAY Researchers were successfully insert ...

03.2019 | THE SCIENTIST 57 CAREERS © ISTOCK.COM, NIKADA H ad he been at almost any other institution in the UK, Hagan Bayley cou ...

58 THE SCIENTIST | the-scientist.com CAREERS 45 in 1993 to 48 in 2010, according to a 2017 PNAS study (114:3879–84). The study’s ...