chemistry1

130 Synthetic Routes to AromaticC-Nitro Compounds Nitrating agent, solvent, temperature, concentration and the ratio of substrat ...

266 Nitramines and Their Derivatives Archibald and co-workers^4 reported the first synthesis of TNAZ (18) in 1989. This route us ...

Nitration 131 heating or cooling. Temperature increase during nitration is often associated with an increase in undesirable by-p ...

Azetidines – 1,3,3-trinitroazetidine 267 Br Br NH 3 Br 25 N 26 N NO 27 NaOH (aq), 80 °C H remove via azeotropic distillation NaN ...

132 Synthetic Routes to AromaticC-Nitro Compounds moderate the nitration step as well as protect the substrate from oxidation. I ...

268 Nitramines and Their Derivatives O 2 NCH 2 OH CH 2 OH CH 2 OH 35 N O 2 N t-Bu NaOH (aq) O 2 NCH 2 NHtBu.HCl CH 2 OH CH 2 OH ...

Nitration 133 Phloroglucinol (25) is more susceptible to oxidation than both phenol and resorcinol. How- ever, its direct nitrat ...

Diazocines 269 Eaton and co-workers^10 synthesized the cubane-based dinitrourea (42) viaN-nitration of the cyclic urea (41) with ...

134 Synthetic Routes to AromaticC-Nitro Compounds Nitration of m-nitroaniline (28) with fuming nitric acid and oleum yields 2,3, ...

270 Nitramines and Their Derivatives HNO 3 , H 2 SO 4 90 % 99 % HNO 3 , Ac 2 O 0–5 °C 96 % HNO 3 , H 2 O 40–45 °C 47 % HNO 3 , H ...

Nitration 135 reconcentrated, but at considerable expense. Another source of pollution is from ‘red water’, the aqueous washing ...

Bicycles 271 H 2 N OH 57 NsHN NHNs OH 58 NNNs O 2 N NO 2 O 62 NNNs OO NOH NNNs OO OO NHNsNsHN Br Br Ns = p-NO 2 C 6 H 4 SO 2 59 ...

136 Synthetic Routes to AromaticC-Nitro Compounds Olah and Lin^47 reported obtaining pure TNB (2) in 50 % yield from the nitrati ...

272 Nitramines and Their Derivatives N COEtEtOC N COEtEtOC BrBr N N N N COEt COEt NO 2 NO 2 N N N N NO 2 NO 2 NO 2 COEt N N N N ...

Nitration 137 NO 2 NO 2 NO 2 NO 2 NO 2 + ++ (1,5-) (1,8-) NO 2 NO 2 NO 2 NO 2 NO 2 (1,3,5-) NO 2 NO 2 (1,4,5-) NO 2 NO 2 (1,3,8- ...

Caged heterocycles – isowurtzitanes 273 The energetic tetranitramine (74) is prepared from the sequentialN-nitration of the bicy ...

138 Synthetic Routes to AromaticC-Nitro Compounds Topchiev^7 has given an extensive discussion of nitrating conditions used, and ...

274 Nitramines and Their Derivatives NN N NN BnBn BnBn Bn Bn CHO CHO +^3 82 (HBIW) CH 3 CN (aq), HCOOH, 25 °C 75–80 % H 2 , Pd/C ...

Nitration 139 is the higher concentration of protonated carboxylic acid in the 100 % sulfuric acid. Studies have shown that nitr ...

Caged heterocycles – isowurtzitanes 275 4,10-diethyl- and 4,10-diformyl- 2,6,8,12-tetraacetyl-2,4,6,8,10,12-hexaazaisowurtzitane ...