Science_-_6_March_2020

protein (GFP) ( 19 ), using adeno-associated virus (AAV) (Fig. 3A) allowed us to visualize their numerous axons projecting to th ...

Kataokaet al.,Science 367 , 1105–1112 (2020) 6 March 2020 3of8 Injection Saline Muscimol Injection –1.0 –0.5 0 0.5 1.0 1.5 2.0 2 ...

Kataokaet al.,Science 367 , 1105–1112 (2020) 6 March 2020 4of8 Fig. 3. Optogenetic stimu- lation of DP/DTT→DMH glutamatergic tra ...

sympathetic stress responses ( 22 ). However, photostimulation of DP/DTT→LH transmis- sion elicited no or subtle changes in the ...

monosynaptic pathway for driving sympathetic stress responses. First, DP/DTT→DMH pro- jection neurons were selectively lesioned. ...

inHR,MAP,andTcore(HR: 63% inhibition, MAP: 52% inhibition,Tcore:66%inhibition; Fig. 4G) as compared with illumination of palGFP- ...

L. J. Robinson, J. M. Law, M. E. Symonds, H. Budge, Exp. Physiol. 101 , 549–557 (2016). J. Parket al.,J. Physiol. 595 , 4893–49 ...

NEURODEVELOPMENT A neurodevelopmental origin of behavioral individuality in theDrosophilavisual system Gerit Arne Linneweber1,2, ...

path details like left- or right shifted angles (Fig. 3A and fig. S5C), distance, full walks, me- ander, absolute horizon deviat ...

reduced genetic diversity affects behavioral stability. We performed repeated testing of DGRP-639andDGRP-859individual flies and ...

Linneweberet al.,Science 367 , 1112–1119 (2020) 6 March 2020 4of8 Fig. 3. Individual variation ofDrosophilaobject orientation re ...

we first asked whether the DCNs were re- quired for object orientation. Inactivating ei- ther all DCNs or only M-DCNs resulted i ...

M-DCN asymmetry have a low aSD, whereas individuals with symmetric M-DCN have a high aSD (Fig. 5, B and C). To test if DCN wirin ...

orientation behavior across individuals. We therefore wondered if the changed object orientation responses in the DGRP strains r ...

similar mechanisms and consequences will hold true in other species, including humans. Previous work inDrosophilavisual behav- i ...

REPORT ◥ LIQUID CRYSTALS Topological structure and dynamics of three-dimensional active nematics Guillaume Duclos^1 , Raymond Ad ...

Ducloset al.,Science 367 , 1120–1124 (2020) 6 March 2020 2of5 microtubule fd virus molecular motor crosslinker E F B p a D A 50 ...

monopole charge or be topologically neutral, depending on its director winding structure. Because charged topological loops can ...

from 2D systems are generalized to discli- nation lines, where the director similarly has apwinding, affording a broader variety ...

REFERENCES AND NOTES S. Galtier,Introduction to Modern Magnetohydrodynamics (Cambridge Univ. Press, ed. 1, 2016). C. Blanch-Mer ...