Nature - USA (2020-01-02)
Extended Data Fig. 2 | Eff icient metastasizers express higher levels of MCT1 than inefficient metastasizers. Related to Fig. 2 ...
Article Extended Data Fig. 3 | See next page for caption. ...
Extended Data Fig. 3 | MCT1 inhibition impairs metastasis without altering MCT1, CD147, CD98 or β 1 -integrin expression levels. ...
Article Extended Data Fig. 4 | MCT1 inhibition with AZD3965 impairs metastasis without altering markers of epithelial-to-mesench ...
Extended Data Fig. 5 | Representative images of the bioluminescence analysis of visceral organs to determine metastatic disease ...
Article Extended Data Fig. 6 | See next page for caption. ...
Extended Data Fig. 6 | shRNA-mediated knockdown of MCT1 inhibits melanoma metastasis in vivo. Related to Fig. 2. a, b, Western ...
Article Extended Data Fig. 7 | CRISPR deletion of MCT1 from mouse melanoma cells impairs metastasis, whereas MCT1 overexpression ...
Extended Data Fig. 8 | See next page for caption. ...
Article Extended Data Fig. 8 | MCT1 inhibition does not impair the migration of melanoma cells in culture but appears to reduce ...
Extended Data Fig. 9 | See next page for caption. ...
Article Extended Data Fig. 9 | Increased MCT1 expression in melanomas is associated with significantly worse patient survival. R ...
Extended Data Fig. 10 | See next page for caption. ...
Article Extended Data Fig. 10 | MCT1 inhibition reduces the levels of PPP, but not glycolytic, metabolites. Related to Figs. 3 ...
1 nature research | reporting summary April 2018 Corresponding author(s): Sean J. Morrison Reporting Summary Nature Research wis ...
2 nature research | reporting summary April 2018 Data Policy information about availability of data All manuscripts must include ...
3 nature research | reporting summary April 2018 Anti-Mouse CD31 (PECAM-1) eFlour 450, clone:390, Cat. #48-0311-82, LOT:1982691 ...
4 nature research | reporting summary April 2018 http://www.thermofisher.com/antibody/product/CD31-PECAM-1-Antibody-clone-390-Mo ...
5 nature research | reporting summary April 2018 http://www.jacksonimmuno.com/catalog/products/711-545-152 Donkey anti-rat IgG, ...
6 nature research | reporting summary April 2018 Field-collected samples No field-collected samples were used. Human research pa ...
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