Science - USA (2021-10-29)
RESEARCH ARTICLE ◥ INDIGENOUS PEOPLES Effects of land dispossession and forced migration on Indigenous peoples in North America ...
lands according to certain perceived quantities and values of natural resources. Centuries of land dispossession have re- shaped ...
Although our current analysis is based on data compiled with these historical limitations, the data still capture a preponderanc ...
the documented historical period (median = 67,289 km^2 ). Without exception, every present- day tribe has a smaller land base t ...
47.7% of tribes saw increased wildfire risk on present-day lands relative to their historical lands. Given that wildfire hazard ...
vary across human history, but all require access to land. Although near-total land reduction (Fig.1andtableS4)affectsfutureagri ...
ongoing collaboration, collection, and refine- ment that builds continually from tribal oral histories, reliable crowdsourcing, ...
T. Ahtone, R. Lee, K. Goodluck, M. Pearce, Land-grab universities. High Country News30 March 2020;www.hcn.org/issues/52.4/ indi ...
RESEARCH ARTICLE SUMMARY ◥ CORONAVIRUS A prenylated dsRNA sensor protects against severe COVID-19 Arthur Wickenhagen, Elena Sugr ...
RESEARCH ARTICLE ◥ CORONAVIRUS A prenylated dsRNA sensor protects against severe COVID-19 Arthur Wickenhagen^1 , Elena Sugrue^1 ...
which have not previously been ascribed anti- viral activity. We exogenously expressed these ISGs in human A549 lung cells modif ...
(Fig. 3, E and F). Thus, OAS3 is not required for OAS1 to instigate a block to SARS-CoV-2 replication. To confirm that OAS1 was ...
Wickenhagenet al.,Science 374 , eabj3624 (2021) 29 October 2021 4 of 18 Protein coding ncRNA pseudogene Mitochondrial RNA misc R ...
observed that OAS1 interacted with several mito- chondrial RNAs (fig. S3), which is consistent withthepresenceofdsRNAinthemitoch ...
Wickenhagenet al.,Science 374 , eabj3624 (2021) 29 October 2021 6 of 18 Actin OAS1 NTC Guide 3Guide 3 NTC Guide 5Guide 5 OAS1 CR ...
structures reminiscent of the endoplasmic reticulum (Fig. 4I), whereas nonprenylated p42 and p46 C397A were diffusely distrib- u ...
pathogen-associated molecular pattern. In the absence of RNase L, SARS-CoV-2 dsRNA colocalized with prenylated OAS1 (Fig. 4, J a ...
Esan, in Nigeria) (Fig. 5C) and could have a major influence on the susceptibility of differ- ent populations to severe COVID-19 ...
reservoirs of SARS-CoV and SARS-CoV-2, and this may contribute to horseshoe bats being such prolific reservoir hosts of Sarbecov ...
fraction of infected individuals (likely mea- sured in“hundreds of thousands”in the UK alone). With the continued emergence of S ...
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