Principles and Practice of Pharmaceutical Medicine

For the patient, knowledge of therapeutic coverage heightens the understanding of the impact of a particular level of compliance ...

27.10 Which forms of partial compliance and noncompliance are particularly relevant? White-coat compliance The patient’s complia ...

drugs, undefined, though progress is being made with studies that define these limits. The key, of course, is to know the drug’s ...

Is the cause pharmacological, due to failure of correctly taken drug to work as hoped, or is the cause due to inadequate complia ...

Thus, the physician who has a reliable measure of the patient’s dosing history can interpret the patient’s response to the drug ...

the physician decided to stop treatment. Now we see that the one patient in five who is ‘holiday- prone’ is abruptly stopping tr ...

is volume dependent, and volume is limited by pricing. For this reason, most of the work done to date with electronic monitoring ...

patient needs. Instead, one can expect a variety of electronically monitored packages to emerge as the recognized need for such ...

detection of poor compliance will improve as the use of electronic monitoring expands. There have been many examples in the past ...

due to seemingly inadequate response to the prescribed drug regimens. If there is one lesson taught by the past decade of resear ...

women with osteoporosis: improving the measure- ments of persistence on actonel treatment: the impact study’. InEuropean Calcifi ...

Sheiner LB. 1997. ‘Learning versus confirming in clinical drug development’.Clin. Pharmacol. Ther. 61 : 275–291. Urquhart J. 199 ...

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28 Monitoring Drug Concentrations in Clinical Practice Anthony W. Fox 28.1 General principles of therapeutic monitoring Measurin ...

The biggest practical issue is taking the sample at the correct time: these times differ for digoxin (6 h post-dose), gentamicin ...

time since ingestion is also predictive of toxicity. Furthermore, concomitant drugs and chronic alcohol abuse can lower the thre ...

Blood gases indicate a mixed picture: pH is low, and HCO 3 is low, due to the direct acidotic challenge of the toxin. pCO 2 i ...

provide examples of quantitative urine concentra- tion monitoring, and enable an assessment of the glomerular filtration rate (G ...

Glauser TA, Pippenger CE. 2000. Controversies in blood-level monitoring: reexamining its role in the treatment of epilepsy.Epile ...

29 Generics J.D. Gabriel LopezandJ.D. Thomas Hoxie Generic drugs are drugs that are sold under their generic name rather than a ...