Science - USA (2022-04-15)
sediments can be used to further extend N availability reconstructions ( 14 ). Likely owing to the strong influence of local urb ...
in net mineralization may be able to counteract this reduction ( 46 , 47 ). In addition to the direct effects of eCO 2 , rising ...
soil N by almost 40% over six decades ( 5 ). Where frequent N losses occur without sub- stantial inputs, such as in most rangela ...
program would involve monitoring of N availability metrics such as N concentrations in plant tissues, net N mineralization in so ...
Collectively, these data could be assembled into an annual state-of-the-N-cycle report that would represent a comprehensive reso ...
for human health and well-being that should be investigated. For example, lower protein concentrations in grazing livestock diet ...
B. S. Ripley, J. Cunniff, C. P. Osborne, Photosynthetic acclimation and resource use by the C 3 and C 4 subspecies ofAlloterops ...
ACKNOWLEDGMENTS We are grateful to A. Carew for graphic design assistance and to J. Penuelas, R. Sabo, M. Engardt, and D. Simpso ...
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RESEARCH ARTICLE SUMMARY ◥ LIPIDOMICS Sphingolipids control dermal fibroblast heterogeneity Laura Capolupo, Irina Khven, Alex R. ...
RESEARCH ARTICLE ◥ LIPIDOMICS Sphingolipids control dermal fibroblast heterogeneity Laura Capolupo^1 , Irina Khven^2 , Alex R. L ...
decreasing CV. Sphingolipids populated the top CV ranking positions, confirming that the sphingolipid pathway (fig. S1F) is subj ...
activities responsible for Cer processing, rather than those producing different Cer backbones, are variable at a cell-to-cell l ...
B4GALT5encoding lactosylceramide synthase (LCS) reduced toxin binding (fig. S2, B and C) without inducing significant toxicity ( ...
by mass imaging (fig. S2, E and F). We then analyzed dHFs derived from four unrelated healthy individuals that displayed an anal ...
Capolupoet al.,Science 376 , eabh1623 (2022) 15 April 2022 6 of 12 AB Cycle G1/S Cycle G1 Cycle G2 Cycle M Cycle M/G1 Middle Bas ...
compared with matched dHFs (Fig. 5, G and H). These data indicate that dHF lipotypes are reflected by fibroblast subtypes popula ...
mechanisms. Therefore, lipotypes are asso- ciated with cell states, yet cell states are not endowed with transcriptional program ...
andCCL2were up-regulated in Gb4S-OE cells and down-regulated in GM3S-OE cells (fig. S8G). Moreover, when reticular and papillary ...
dHFs and bulk RNA-seq on five cell populations isolated by FACS according to their lipid com- position were performed. Skin tiss ...
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