Catalyzing Inquiry at the Interface of Computing and Biology

ILLUSTRATIVE PROBLEM DOMAINS AT THE INTERFACE OF COMPUTING AND BIOLOGY 319 disorders are highly penetrant, but occur relatively ...

320 CATALYZING INQUIRY studies in detecting genetic contributions to the likelihood of various diseases with at least partial en ...

ILLUSTRATIVE PROBLEM DOMAINS AT THE INTERFACE OF COMPUTING AND BIOLOGY 321 individuals that are deficient in thiopurine S-methyl ...

322 CATALYZING INQUIRY Science (NIGMS), PharmGKB is a publicly available, Internet-accessible database for pharmacogenetics and ...

ILLUSTRATIVE PROBLEM DOMAINS AT THE INTERFACE OF COMPUTING AND BIOLOGY 323 More generally, Watkins et al. point out that the goa ...

324 CATALYZING INQUIRY Spatial registration and alignment of instruments, the surgeon’s hands, and the digital body being oper- ...

ILLUSTRATIVE PROBLEM DOMAINS AT THE INTERFACE OF COMPUTING AND BIOLOGY 325 9.9 COMPUTATIONAL THEORIES OF SELF-ASSEMBLY AND SELF- ...

326 CATALYZING INQUIRY more expressive form of self-assembly is required. Ideally, a designer could select a set of components a ...

ILLUSTRATIVE PROBLEM DOMAINS AT THE INTERFACE OF COMPUTING AND BIOLOGY 327 attempting to connect to an established shape is prop ...

328 CATALYZING INQUIRY biological data. This fact—that an understanding of biological systems depends on so many different kinds ...

ILLUSTRATIVE PROBLEM DOMAINS AT THE INTERFACE OF COMPUTING AND BIOLOGY 329 ment is that sequence complexity will be highly corre ...

330 CATALYZING INQUIRY degree of structure or pattern in that entity; and physical complexity, which interprets the shared Kolmo ...

CULTURE AND RESEARCH INFRASTRUCTURE 331 331 10 CULTURE AND RESEARCH INFRASTRUCTURE Earlier chapters of this report have focused ...

332 CATALYZING INQUIRY of the barriers that affect research at the BioComp interface. Chapter 11 is devoted to proposing possibl ...

CULTURE AND RESEARCH INFRASTRUCTURE 333 10.2.2 Education and Training, Education, either formal or informal, is essential for pr ...

334 CATALYZING INQUIRY has noted that “biologists are biologists because they love living things. A computation is not alive.”^4 ...

CULTURE AND RESEARCH INFRASTRUCTURE 335 mathematics, physics, chemistry, and biology as a block, taught by a team of dedicated p ...

336 CATALYZING INQUIRY ence majors should be exposed to engineering principles and analysis, should receive quantitative trainin ...

CULTURE AND RESEARCH INFRASTRUCTURE 337 10.2.2.3.3 Computer Science Finally, the BIO2010 report noted the importance of informat ...

338 CATALYZING INQUIRY Box 10.2 Essential Concepts of Mathematics and Computer Science for Life Scientists Calculus Complex num ...