Microfluidics for Biologists Fundamentals and Applications

Fabrication of dissolvable film tabs requires an adhesive solid support like PSA (Fig.5.17). First, the knife cutter is used to ...

7 Assembly It is necessary to carefully remove all segments of PSA and PMMA that have been cut from the main disk layer, this is ...

then rolled at room temperature in the hot roll laminator, ensuring that the disk is void of trapped air bubbles (Fig.5.22). Thi ...

7.2 Microchannels (PSA) A layer of PSA directs fluid from each chamber towards further unit operations as the disc spin rate is ...

the above layers to those below as well as creating access points for the fluid to come in contact with the dissolvable tabs con ...

spin rates are known it is possible to create an automated programme to control the change in spin rate at specific times throug ...

of blood, can be entirely automated using nothing more than a spindle motor and preprogrammed spin rate, leading to a visually i ...

Nwankire CE et al (2013b) Full integration of a liver assay panel on a centrifugal microfluidic platform. In: 2013 Transducers ...

Gorkin R III, Nwankire CE, Gaughran J, Zhang X, Donohoe GG, Rook M, O’Kennedy R, Ducre ́e J (2012) Centrifugo-pneumatic valving ...

Chapter 6 Materials and Surfaces in Microfluidic Biosensors Pandiaraj Manickam, Jairo Nelson, and Shekhar Bhansali 1 Introductio ...

1.1 Biosensors-Involvement of Microfluidics According to a recent National Institute of Health (NIH) report, point-of-care (POC) ...

2 Material Development for Microfluidic Systems The choice of materials for microfluidic sensor fabrication is a significant fac ...

and well-established micromachining processes [ 10 , 11 ]. Furthermore, both the materials can be chemically modified and functi ...

Si microcantilevers and optical resonators have recently been interfaced with microfluidics for optical sensing (Fig.6.3). Silic ...

reaction (PCR) and for bioreactions. However, silicon substrates are relatively expensive when compared with other materials, su ...

One pitfall of utilizing silicon and glass substrates is the costly conditions under which the micromachining of channels and st ...

Fig. 6.4 Microfluidic valve network. Photograph of the multiplexed latching valve test device, with a four-bit demultiplexer [ 1 ...

they have become the most commonly used microfluidic materials. Based on their physical properties, polymers can be classified i ...

2.2.2 Thermoplastics Thermoplastics are a class of synthetic polymers that exhibit softening behavior above a characteristic gla ...

coupled with electrophoretic separation in a PMMA-integrated microdevice [ 31 ]. Chen et al., reported a self-contained, integra ...