Science - USA (2022-05-27)
(fig. S4). Sedimentation is periodically inter- rupted by large floods, which cause an erosional wave to propagate from the rive ...
these rivers is statistically different (one-way ANOVA test,P = 0.001), indicating that the observedLAvariability is not driven ...
ENVIRONMENTAL TOXINS Models predict planned phosphorus load reduction will make Lake Erie more toxic Ferdi L. Hellweger^1 , Robb ...
The model includes generation of H 2 O 2 , damage to enzymes by H 2 O 2 , and two H 2 O 2 - management systems, including protec ...
H 2 O 2 readilydiffusesacrosscellmembranes, and the model predicts that degradation by the nontoxigenic strain leads to lower ex ...
MC concentration decreases with rising tem- perature (Fig. 4B, part 2, CTRL). These results and observations of lower temperatur ...
J. J. Morris, Z. I. Johnson, M. J. Szul, M. Keller, E. R. Zinser,. PLOS ONE 6 , e16805 (2011). L. Lei, C. Li, L. Peng, B.-P. Ha ...
ANTIBIOTIC DISCOVERY Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance Zon ...
synthesis of macolacin, a colistin analog that is effective against pathogens that express the mcr-1resistance gene ( 6 ). In th ...
thesestrains.Wehavecalledtheactivestruc- ture cilagicin (Fig. 1E). Cilagicin was active against all Gram- positive pathogens tha ...
metabolite(s) that interacts with cilagicin, we screened a series of lipid II intermediates for their ability to suppress cilagi ...
P. mucilaginosus. The genusPaenibacillusis Gram variable.P. mucilaginosus’sreported negative Gram staining suggests that it con- ...
study of syn-BNPs that are inspired by un- explored BGC families should prove to be a productive strategy for identifying distin ...
IMMUNOLOGY The CD8a–PILRainteraction maintains CD8 T cell quiescence Linghua Zheng^1 ,XueHan^1 ,ShengYao^1 ,YuwenZhu^1 ,John ...
PILRais a transmembrane protein broadly expressed on myeloid cells, including macro- phages, dendritic cells, and neutrophils ( ...
decreased 2 days after 9B12 treatment (fig. S18D). In a complementary approach, treat- ment with 9B12 reduced the absolute numbe ...
This is reminiscent of B7’s interactions with both CD28 (promoting T cell activation) and CTLA-4 (suppressing T cell activation) ...
provide greater understanding of how naïve and memory T cell repertoires are main- tained and persist in normal and patholog- ic ...
Molecular Discovery, and Flow Cytometry Core Facility for their technical support.Funding:This study is partially funded by the ...
BIOMEDICINE A transient, closed-loop network of wireless, body-integrated devices for autonomous electrotherapy Yeon Sik Choi1,2 ...
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