Science - USA (2019-01-04)
Challenger observations ( 18 ). More generally, OPT-0015 indicates that the upper 2000 m of the ocean has been gaining heat sinc ...
23.S.G.Purkey,G.C.Johnson,J. Clim. 23 , 6336– 6351 (2010). D. G. Desbruyères, S. G. Purkey, E. L. McDonagh, G. C. Johnson, B. A ...
VIROLOGY Metagenomic sequencing at the epicenter of the Nigeria 2018 Lassa fever outbreak L. E. Kafetzopoulou1,2,3, S. T. Pullan ...
average frequency of 4.26% with a maximum of 42.9%, allowing for sufficient genomic sequence (>70%) for phylogenetic comparis ...
significantly differently in the L and S segments (supplementary methods), which is in line with the small number of potential L ...
A request for information on circulating strains was made on 28 February at the height of the outbreak; within 10 days, our pilo ...
PALEONTOLOGY An elephant-sized Late Triassic synapsid with erect limbs Tomasz Sulej^1 and Grzegorz Niedźwiedzki^2 * Here, we des ...
of the largest bones ofLisowiciasuggests that the studied material represents either a fast- growing taxon or juvenile/subadult ...
to that observed in the evolution of herbivorous dinosaurs in the Mesozoic and mammalian line- ages in the mid-late Paleogene ( ...
EVOLUTION DNA fragility in the parallel evolution of pelvic reduction in stickleback fish Kathleen T. Xie1,2,3, Guliang Wang^4 , ...
Xieet al.,Science 363 ,81–84 (2019) 4 January 2019 2of4 AB Marine Pel region Freshwaterpelvic-reduced Pel region Marine RC regio ...
number changes seen in the topoisomer assays above). TG-repeats aloneinduced mobility shifts in topoisomer assays (Fig. 3B) ( 18 ...
ancient standing variants provide an alternative way to overcome the demographic constraints of waiting for de novo mutations in ...
PROTEIN TRANSLOCATION Structure of the posttranslational Sec protein-translocation channel complex from yeast Samuel Itskanov^1 ...
Itskanovet al.,Science 363 ,84–87 (2019) 4 January 2019 2of4 Fig. 3. A fully opened Sec61 channel in the Sec complex.(AandB)Stru ...
A to G) but contains unusually long A-B, B-C, and D-E interstrand loops (fig. S3, B and C). With both A-B and B-C loops, FN3 cre ...
structurealsoallowsustoproposehowBiPHsp70 may catch the substrate in the ER lumen. Despite the low resolution of the J domain (F ...
PROKARYOTIC IMMUNITY Functionally diverse type V CRISPR-Cas systems Winston X. Yan^1 , Pratyusha Hunnewell^1 , Lauren E. Alfonse ...
Yanet al.,Science 363 ,88–91 (2019) 4 January 2019 2of4 Fig. 1. Discovery and screening of type V CRISPR-Cas diversity.(A) Class ...
amino acids) and Cas12i (1033 to 1093 amino acids), respectively. These effectors show distant similarity to Cas12b, with substa ...
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