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Extended Data Fig. 1 | Screening for GPCR–βarr1 complexes. A fluorescence size-exclusion chromatography (FSEC) approach was used ...
Article Extended Data Fig. 2 | Phosphorylation of NTSR1 is crucial for the coupling of βarr1. a, The phosphorylation state of NT ...
Extended Data Fig. 3 | See next page for caption. ...
Article Extended Data Fig. 3 | Overview of sample preparation and representative cryo-EM preparation. a, Workf low for the assem ...
Extended Data Fig. 4 | See next page for caption. ...
Article Extended Data Fig. 4 | Mass spectrometry analysis of crosslinks in the NTSR1–βarr1(ΔCT) complex. a, Lysine residues modi ...
Extended Data Fig. 5 | Cryo-EM workf low. Flow chart of cryo-EM data analysis. Global resolution was determined by FSC with a cu ...
Article Extended Data Fig. 6 | Cryo-EM map resolution and model validation, with multi-body analysis revealing structural hetero ...
Extended Data Fig. 7 | Arrestin orientation and interdomain twist. a, Additional views of Fig. 1c, showing an overlay between NT ...
Article Extended Data Fig. 8 | See next page for caption. ...
Extended Data Fig. 8 | Identification of GRK5 phosphorylation sites in human NTSR1 and comparison of phosphate-specific contacts ...
Article Extended Data Fig. 9 | Membrane context and curvature for NTSR1– βarr1(ΔCT). a, Comparison of the structures of NTSR1–βa ...
Extended Data Table 1 | Cryo-EM data collection, refinement and validation statistics ...
1 nature research | reporting summary October 2018 Corresponding author(s): Brian K. Kobilka, Georgios Skiniotis Last updated by ...
2 nature research | reporting summary October 2018 Field-specific reporting Please select the one below that is the best fit for ...
Nature | Vol 579 | 12 March 2020 | E7 Corrections & amendments Author Correction: Bile acid metabolites control TH17 and Tre ...
E8 | Nature | Vol 579 | 12 March 2020 Corrections & amendments Publisher Correction: Modular and tunable biological feedback ...
O verly technical language in science articles doesn’t just muddy the waters for non-experts — it can alienate readers, potentia ...
I n 2010, after obtaining my master’s degree in Germany, I moved to Mexico to pursue my PhD in ecology and sustainable develop m ...
Photographed for Nature by Jennie Lyn Pretorius. Where I work Rose A. Marks I study how plants adapt to some of the most extreme ...
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