Science - USA (2021-12-03)

REVIEW SUMMARY ◥ DEVELOPMENTAL BIOLOGY The primitive streak and cellular principles of building an amniote body through gastrula ...

REVIEW ◥ DEVELOPMENTAL BIOLOGY The primitive streak and cellular principles of building an amniote body through gastrulation Guo ...

gastrulation as commonly seen in triploblastic animals. Nevertheless, comparative genomics and molecular phylogeny studies have ...

functional diversification is fundamental to multicellularity and that specification of cells dedicated to nutritional acquisiti ...

among all amniote clades: (i) Internalization of mesoderm- and endoderm-fated cells takes place in a circumferentially restricte ...

extraembryonic cell lineages) and is the pri- mary interface for fetal-environmental (includ- ing fetal-maternal) exchanges. Exc ...

flows of cells toward the posterior of the em- bryo (Fig. 4B). Furthermore, the marginal tensile ring may well act to regulate g ...

primitive streak in these 2D gastruloids ( 74 ). However, it is not clear that these movements are related to the presence of a ...

argument was that the primitive streak, formed after ~14 days of human development post- fertilization, represented a definitive ...

J. Rossant, P. P. L. Tam, Exploring early human embryo development.Science 360 , 1075–1076 (2018). doi:10.1126/ science.aas9302 ...

Yes, I would like more informationaboutjoiningthe AAAS 1848 Society. PLEASECONTACT MEAT: Name: Address: City: State: Zip code: C ...

RESEARCH ARTICLE SUMMARY ◥ CORONAVIRUS mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern Rishi R. ...

RESEARCH ARTICLE ◥ CORONAVIRUS mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern Rishi R. Goel1,2 ...

vaccine compared with a group of SARS- CoV-2–recovered vaccinees generating recall responses from preexisting immunity. These an ...

Peak levels of anti-spike and anti-RBD immuno- globulin G (IgG) were observed 1 week after the second vaccine dose and subsequen ...

Goelet al.,Science 374 , eabm0829 (2021) 3 December 2021 4of17 Spike+ IgG+ Spike+ IgM+ Spike+ IgA+ (^0) 0.50.75 (^1360) 0.50.75 ...

neutralization titers correlated with both anti- spike IgG and RBD-ACE2 binding inhibition (fig. S3, A to D). The neutralization ...

Goelet al.,Science 374 , eabm0829 (2021) 3 December 2021 6 of 17 B.1.1.7+ B.1.351+ B.1.617.2+ Infectio n Recovere d Naiv e WT RB ...

trimer, potentially allowing for increased recruitment and/or selection of specific clones that can bind conserved regions of RB ...

and four SARS-CoV-2–recovered individuals at 3 to 4 months postvaccination (Fig. 4A and fig. S5A). Consistent with our previous ...