Science - USA (2021-12-03)

quaternary C(sp^3 ) centers ( 11 ). However, despite broad biochemical relevance, SH2-based cross- coupling paradigms remain eff ...

carbons, and these methods typically rely on highly reactive tertiary Grignard reagents or alkyl iodide electrophiles ( 33 – 36 ...

underscoring the capacity of the SH2 mecha- nism to generally construct sterically hin- dered centers. Redox-active esters conta ...

medicinally important cyclic sulfone ( 22 to 24 , 47% to 63% yield) ( 41 ). Fora-oxy esters, radicals generated adjacent to both ...

and ethyl could be introduced into sp^3 scaf- folds in high efficiency ( 30 to 33 , 59% to 84% yield). Methyl bromide was genera ...

NANOPHOTONICS Continuous-wave frequency upconversion with a molecular optomechanical nanocavity Wen Chen^1 , Philippe Roelli^1 , ...

resonantly drives a mechanical oscillator, itself parametrically coupled to a laser-driven optical cavity,whichresultsinmodulati ...

to match the vibration frequency of BPhT atnm≃32.4 THz. When a pump laser tuned at 405 THz (740 nm) is focused on the sample (Fi ...

of the upconverted Raman signal from 0.1 to 100mW (green circles in Fig. 3A), which is consistent with the expected parametric u ...

NANOPHOTONICS Detecting mid-infrared light by molecular frequency upconversion in dual-wavelength nanoantennas Angelos Xomalis^1 ...

on self-assembled molecular monolayers with discrete vibrational absorption modes in the l=6to12mm range. Coupling requires matc ...

much faster than the QCL pulse repetition rate (5ms). To better quantify the upconversion effi- ciency, we measured the percenta ...

B. Schwarzet al.,Nat. Commun. 5 , 4085 (2014). P. Roelli, D. Martin-Cano, T. J. Kippenberg, C. Galland, Phys. Rev. X 10 , 03105 ...

follow-up ground-based photometry and found no contamination from eclipsing binaries up to 2.5 arc sec from the target star ( 9 ...

SCIENCEscience.org 3 DECEMBER 2021¥VOL 374 ISSUE 6572 1273 Table 1. Properties of host star GJ 367 and planet GJ 367b.The stella ...

Modeller ( 13 ), to model the transit photometry and RV data simultaneously ( 9 ). Table 1 re- ports the physical properties of ...

Processing and Analysis Consortium (DPAC) (www.cosmos.esa. int/web/gaia/dpac/consortium). Funding for DPAC has been provided by ...

indications that regional fluxes vary subs- tantially on decadal time scales ( 7 , 11 , 12 ), it is essential to develop more-ro ...

three times larger than that inDyCO 2. Var- iation in drawdown intensity across stations contributing toDyCO 2 likely reflects d ...

campaigns flown in March to November together (Fig. 3B). For the surface data, we find a signif- icant positive relationship bet ...