Comparative and Veterinary Pharmacology

of beef cattle, for example, the EMEA recommends at least twelve animals (four groups of three animals) whereas the FDA CVM reco ...

Analysing for Residues of Veterinary Drugs in Depletion Studies Methods of analysis for veterinary drug residues are required fo ...

the dietary exposure of consumers to injection site residues, and therefore any risks associated with ingestion, they frequently ...

animals being treated daily for 7 days with an antibiotic and, from official sales data, an estimate that 11.92% of these animal ...

depletion data set, or shortcomings in the studies, by adding an extra safety period. A third method established withdrawal peri ...

distribution of log residue concentrations at each time. Estimates are made of between-animal variance and of measurement error ...

method relates to the concentration of residues and the TTSC, respectively. The strength of the TTSC approach is that an assumpt ...

veterinary chemical product. In both situations, residues deplete to below the LOQ of the analytical method. An ESI which is sho ...

2.3 Risk Communication A critically important aspect of a food safety risk analysis is an effective two-way exchange of informat ...

(FAO–WHO 1996 ). Surveillance programmes, in contrast, sample tissues from animals suspected of violative residues on the basis ...

products, better injection techniques have resulted in less wastage of edible meat tissue as a result of trimming blemishes. Vet ...

detect and quantify the residues of these compounds. A separate issue relates to limitations of the conventional NOEL-safety fac ...

AcknowledgementsThe author wishes to thank APVMA Science Fellows Emeritus Prof. Jock McLean, Dr Dieter Arnold and Prof. Terry O’ ...

Freidlander LG, Brynes SD, Ferna ́ndez AH (1999) The human food safety evaluation of new animal drugs. Veterinary Clinics of Nor ...

Veterinary Medicines and the Environment Alistair B.A. Boxall Contents 1 Introduction .......................................... ...

KeywordsVeterinary medicines
Environmental fate
Ecotoxicity
Environmental risk 1 Introduction Following administration to ...

environment through removal and subsequent disposal of waste material (including manure/slurry and “dirty” waters), via excretio ...

housing and manure production characteristics, the emission and distribution routes for veterinary medicines are essentially sim ...

Bacterial infections in fish are usually treated using medicated food pellets which are added directly to pens or cages (Samuels ...

many pesticides), the difference in sorption of a given compound in different soils cannot be explained by variations in soil or ...