Science - USA (2022-02-25)

STRUCTURAL BIOLOGY Dynamics and mechanism of a light-driven chloride pump Sandra Mous^1 , Guillaume Gotthard1,2, David Ehrenberg ...

similar affinity as chloride [Cl–:Kd= 24 mM; Br–:Kd=10mM( 17 )]. Furthermore, struc- tural studies show that a bromide ion is co ...

( 28 ). We therefore probed the rise and decay of spectroscopic states (Fig. 1B) in crystals by time-resolved absorption spectro ...

to C). The C20 methyl group of the isomerized retinal pushes against Trp^201 ,shiftingitaway by 0.4 Å. Trp^99 shifts by 0.3 Å to ...

that an intermediate state with sodium cap- tured between retinal and helix C could lead to similar kink formation in KR2. InNmH ...

atDt=12.5ms(fig.S18B).Oncethehalidedif- fuses into the Wat^409 position, the transport path- way is occluded by Asp^231 (Fig. 5C ...

ofNmHR (fig. S22D), indicating that the so- dium and chloride transport pathways may partially overlap on the extracellular side ...

NANOMATERIALS Highly stretchable van der Waals thin films for adaptable and breathable electronic membranes Zhuocheng Yan^1 , Do ...

by the Young’s modulus and the membrane thickness following the relationship p^2 4 P^20 1 v^21 E 1 þ 1 v^22 E 2 "# 2 1 = 3 þ p ...

applications usually show worse mechanical properties owing to their specific structural properties, such as chain length, regio ...

other to form broad-area plane-to-plane VDW interfaces with an average of ~3 to 4 nanosheets staggered in a crisscross manner in ...

The ability of a membrane to make a con- formal interface with the surface topography can be determined by bending stiffness ( 2 ...

In this measurement, the VDWTF pad is placed on the left forearm and the gate electrode is adhered on the symmetrical position ( ...

signal measured by the skin-gate transistor (Fig. 5K), showing the dynamic activity of the alpha rhythm coupled with cyclic eye ...

X. Fang, C. Zhang, X. Chen, Y. Wang, Y. Tan,ActaMech. 226 , 1657 – 1672 (2015). S. Wangetal.,J.Appl.Mech. 79 , 031022 (2012). Y ...

generate a highly functional and persistent ILC3 subset, which we refer to hereafter as “trained ILC3s”(Tr-ILC3s). Enhanced Tr-I ...

SCIENCEscience.org 25 FEBRUARY 2022¥VOL 375 ISSUE 6583 861 Fig. 2. Tr-ILC3s show long-term persistence.(A) Experimental design f ...

can be adoptively transferred and can operate in a T cell–independent fashion during path- ogen rechallenge. Although antigen sp ...

involved in the intestinal epithelial response ( 28 ). We found enhanced ILC3 responses after rechallenge withL. monocytogenes(C ...

CORONAVIRUS Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement Matthew McCallum^1 †, Nadine Czudnocho ...