Biology of Disease
small amounts of hydrogen peroxide produced by CGD patients makes them resistant to catalase negative bacteria. However, catalas ...
the alternative pathway activation. Activation of the lectin pathway requires MBL, MBL-associated serine proteases (MASP) 1 and ...
Deficiencies in the classical and the alternative pathways can be detected in the laboratory by carrying out the CH 50 and AP 50 ...
AUTOIMMUNE DISORDERS CZhhVg6]bZY!BVjgZZc9Vlhdc!8]g^hHb^i]:YLddY &&& Many, but not all, autoimmune disorders ...
X]VeiZg*/ DISORDERS OF THE IMMUNE SYSTEM &&' W^dad\nd[Y^hZVhZ ELISA (Chapter 4). Immunohistochemical techniques (Chap ...
Both insulin dependent diabetes mellitus Type 1 and Addison’s disease are discussed extensively in Chapter 7. The former is caus ...
autoimmune disease, it shows a predominance in males, with younger males generally presenting with both lung and kidney involvem ...
AUTOIMMUNE DISORDERS CZhhVg6]bZY!BVjgZZc9Vlhdc!8]g^hHb^i]:YLddY &&* Joint capsule Synovial fluid Synovial membr ...
A) B) SSSSSS SS SS SS SS SS SS SS SS SS SS SS SS SS SS SS SS SS SS RF RF Sensitized SRBC Agglutination SRBC SRBC SRBC SRBC S ...
difficulties with diagnosis, so it must take full account of the range of presentations. Diagnosis can be helped by demonstratin ...
factor and the presence of antibodies against cardiolipin may also be present, although these are not specific for SLE. Systemic ...
The different manifestations (Table 5.13) of Type I depend on the degree of previous exposure to the allergen and also on the ro ...
Type I hypersensitivity is the most common form of the immunological hypersensitivities and is estimated to affect between one i ...
IMMUNOLOGICAL HYPERSENSITIVITY CZhhVg6]bZY!BVjgZZc9Vlhdc!8]g^hHb^i]:YLddY &'& x 1200 Figure 5.12 The house dust ...
occupational diseases, in which workers are exposed to air-borne immunogens. A typical example of this disorder is Farmer’s lung ...
SUMMARY CZhhVg6]bZY!BVjgZZc9Vlhdc!8]g^hHb^i]:YLddY &'( CASE STUDY 5.1 George is a nine-month-old boy who has suffer ...
reactivity fail. These diseases can be organ specific or systemic. They can be treated with immunosuppressive drugs, although th ...
Further Reading Chapel, H, Haeney, M, Misbah, S and Snowden, N (1999) Essentials of Clinical Immunology, 4th edn. Blackwell Scie ...
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&', X]VeiZg+/ TRANSFUSION AND TRANSPLANTATION 6.1 Introduction Blood transfusion is the transfer of blood or blood products ...
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