Organic Chemistry

PROBLEM 9 Indicate whether each functional group of the five heterocyclic bases in nucleic acids can function as a hydrogen bond ...

048 CHAPTER 27 Nucleosides, Nucleotides, and Nucleic Acids Figure 27.9N The three helical forms of DNA. PROBLEM 11 The phosphodi ...

Section 27.9 Biosynthesis of DNA: Replication 049 thymine–adenine cytosine–guanine sugar sugar major groove minor groove sugar s ...

050 CHAPTER 27 Nucleosides, Nucleotides, and Nucleic Acids Severo Ochoawas the first to prepare synthetic strands of RNA by incu ...

Section 27.11 Ribosomal RNA 051 5 ′ 5 ′ 3 ′ 5 ′ 3 ′ 3 ′ T A T A T A G UCUCGAUACACG OH T A C G C G C G T A C G T A C G C G G C G ...

052 CHAPTER 27 Nucleosides, Nucleotides, and Nucleic Acids 3 ′ a. 5 ′ OH anticodon U G C C C G G C U C AGGC C C G C A A C C C A ...

Section 27.12 Transfer RNA 053 AMP ATP O O O P O− O O P O− O −O O O P O− O P O− O− −O OH O P O− −O O P O− O O O P O− O O O O P O ...

054 CHAPTER 27 Nucleosides, Nucleotides, and Nucleic Acids Table 27.2 The Genetic Code Middle position UCA G U Phe Ser Tyr Cys U ...

Section 27.13 Biosynthesis of Proteins: Translation 055 confuse transcription and translation—these words are used just as they ...

056 CHAPTER 27 Nucleosides, Nucleotides, and Nucleic Acids amino acid transcription modification of RNA 1 5 translation mRNA nuc ...

PROBLEM 18 If methionine is the first amino acid incorporated into a heptapeptide, what is the sequence of the amino acids enco ...

058 CHAPTER 27 Nucleosides, Nucleotides, and Nucleic Acids ANTIBIOTICS THAT ACT BY INHIBITING TRANSLATION Puromycin is a natural ...

Section 27.15 Determining the Base Sequence of DNA 059 If a cytosine in DNA is deaminated to a uracil, uracil will specify incor ...

060 CHAPTER 27 Nucleosides, Nucleotides, and Nucleic Acids Frederick Sanger(Section 23.12) and Walter Gilbertshared half of the ...

Section 27.16 Laboratory Synthesis of DNA Strands 061 The chain-terminated fragments obtained from each of the four experiments ...

062 CHAPTER 27 Nucleosides, Nucleotides, and Nucleic Acids Phosphoramidite Monomers One current method synthesizes oligonucleoti ...

Section 27.16 Laboratory Synthesis of DNA Strands 063 Tutorial: Oligonucleotide synthesis with phosphoramidites O O O N base O O ...

064 CHAPTER 27 Nucleosides, Nucleotides, and Nucleic Acids The groups of cytosine, adenine, and guanine are nucleophiles and the ...

Section 27.16 Laboratory Synthesis of DNA Strands 065 are not needed. However, the yields are not as good. The H-phosphonate mon ...

066 CHAPTER 27 Nucleosides, Nucleotides, and Nucleic Acids Notice that in the phosphoramidite method an oxidation is done each t ...