Stem Cell Processing (Stem Cells in Clinical Applications)

27 Oviedo 4.IV.1997 Chapter V—Scientifi c Research Article 18—Research on embryos in vitro. http://conventions.coe.int/Treaty/EN ...

28 Science. doi: 10.1038/stemcells.2008.21. http://www.nature.com/stemcells/2008/0801/080117/ full/stemcells.2008.21.html. Acces ...

29 Hinxton Group (2010) Statement on policies and practices governing data and material sharing and intellectual property in ste ...

30 International Society for Stem Cell Research (ISSCR) (2015) http://www.isscr.org/. Accessed 10 May 2015 International Stem Ce ...

31 conditions research on human embryo and embryonic stem cells. http://www.legifrance.gouv. fr/affichTexte.do?cidTexte=JORFTEXT ...

32 (2005). Human stem cells, cloning and research. http://www.tenk.fi /en/publications/ HumanStemCellsCloningandResearch.pdf. Ac ...

33 Normile D, Vogel G, Couzin J (2006) South Korean team’s remaining stem cell claim demolished. Science 311(5758):156–157 Nöthl ...

34 Registry of Provenance of Human Embryonic Stem Cell Lines (2013) ISSCR. http://nas-sites.org/ iascr/fi les/2013/01/ISSCRRegis ...

35 Tashibana M, Amato P, Sparman M et al (2013) Human embryonic stem cells derived by somatic cell nuclear transfer. Cell 153(6) ...

© Springer International Publishing Switzerland 2016 37 P.V. Pham (ed.), Stem Cell Processing, Stem Cells in Clinical Applicatio ...

38 The fi rst identifi ed source of MSCs was bone marrow. MSCs are currently isolated from many different tissues in the body, s ...

39 Table 2.1 Human MSC sources , cell surface markers, and expansion media with serum supplements Source Method of isolation Med ...

40 Table 2.1 (continued) Source Method of isolation Media Serum supplement Cell surface markers References Positive Negative Sub ...

41 stem cell therapy for degenerative diseases. However, the immune modulation capacity of MSCs has been the subject of recent i ...

42 muscle, and skin. Using in vitro assays, MSCs have been successfully differentiated into osteoblasts (Castren et al. 2015 ; G ...

43 Table 2.2 Immunomodulatory effec ts of MSCs on immune cells Immune cell type MSCs’ effects T lymphocyte Suppress T-cell proli ...

44 T lymphocytes (Aggarwal and Pittenger 2005 ; Di Nicola et al. 2002 ; English et al. 2009 ), B lymphocytes (Asari et al. 2009 ...

45 Table 2.4 Allogeneic mesenchymal stem cell-based products approved by several countries Names of products Components For dise ...

46 acute MI. There were no adverse reactions or major cardiac events. There was an improvement in left ventricular (LV) ejection ...

47 regeneration. Autologous ADSCs have been successfully applied in osteoarthritis treatment. Stromal vascular fraction as non-e ...