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(Fig.4.3f). All animal procedures conformed to US National Institutes of Health guidelines and were approved by Harvard Universi ...
The cell-coated mesh nanoES was then gently lifted from the SiO 2 substrate using fine forceps, rolled onto a polystyrene or gla ...
fiber scaffolds were labeled by physical absorption of rhodamine 6G from an aqueous solution. Hematoxylin-eosin and Masson trich ...
beam lithography. Previously discussed mechanics-driven self-organization created a random or regular network of 3D features tha ...
Fig. 4.6 3D self-organized nanowire nanoES.a3D reconstructed confocalfluorescence images of self-organized nanoES viewed along y ...
addition, the nanowires (Fig.4.7a, 1), metal interconnects (Fig.4.7a, 2), and SU-8 structural elements (Fig.4.7a, 3) had an area ...
4.3.2 Mechanics-Driven 3D Self-organization We have carried out simulations of a subunit of the self-organized structure (Fig.4. ...
Fig. 4.10 Design and fabrication of self-organized nanoES.aSimulation shows that when the equivalent bending moment is increased ...
4.3.3 NanoES/Tissue Scaffold Hybrids................... The self-organized and mesh nanoES also were merged with conventional ma ...
the pure alginate scaffold prepared under similar conditions. Finally, optical microscopy images of a multilayered mesh nanoES/P ...
Extended studies will be needed to evaluate the nanoES for longer-term implants, although the major component of nanoES, SU-8, h ...
Fig. 4.14 NanoES innervated synthetic cardiac patch. a, bImages showing a-actinin of cardiomyocytes (green ina–e, Alexa Fluor®48 ...
4.3.5 Monitoring of Cell Activity Change to External Stimulations We demonstrated the electrical recording capabilities of nanoE ...
4.3 Results and Discussion 57 ...
The peak amplitude, shape, and width are consistent with extracellular recordings from cardiomyocytes [ 20 ]. We investigate the ...
nanoES/HASMC sheets (Fig.4.18b) were rolled into multi-layer 3D tubular structures and matured without macroscopic delamination ...
We demonstrated the potential of this vascular construct to function as a biomedical device by a 3D pH sensing experiment (Fig.4 ...
4.4 Conclusion......................................... The nanoES concept and implementations described here represent a new di ...
Bibliography Na K et al (2011) Directing zeolite structures into hierarchically nanoporous architectures. Science 333:328– 332 ...
Timoshenko S, Woinowsky-Krieger S (1959) Theory of plates and shells, 2nd edn. McGraw-Hill Inc., p 4– 6 28.http://www.genlantis ...
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