Computational Systems Biology Methods and Protocols.7z

Computational Systems Biology Tao Huang Editor Methods and Protocols Methods in Molecular Biology 1754 ...

METHODS INMOLECULARBIOLOGY Series Editor John M. Walker School of Life and Medical Sciences University of Hertfordshire Hatfield ...

Computational Systems Biology Methods and Protocols Edited by TaoHuang Shanghai Institutes for Biological Sciences, Chinese Acad ...

Editor Tao Huang Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai, China ISSN 1064-3745 ISSN 194 ...

Preface With the rapid development of high-throughput technologies, such as next-generation sequencing and single-cell sequencin ...

Contents Preface. .................................................................... v Contributors........................... ...

17 Single-Cell Protein Assays: A Review ...................................... 293 Beiyuan Fan, Junbo Wang, Ying Xu, and Jian Ch ...

Contributors ADENIYIC. ADEOLA  State Key Laboratory of Genetic Resources and Evolution, Kunming, Yunnan, China; China-Africa Ce ...

KAIHE  State Key Laboratory of Genetic Resources and Evolution, Kunming, Yunnan, China LINHE  Key Laboratory for the Genetics ...

ROBERTW. MURPHY  State Key Laboratory of Genetic Resources and Evolution, Kunming, Yunnan, China; Centre for Biodiversity and C ...

YA-PINGZHANG  State Key Laboratory of Genetic Resources and Evolution, Kunming, Yunnan, China; Yunnan Laboratory of Molecular B ...

Chapter 1 DNA Sequencing Data Analysis Keyi Long, Lei Cai, and Lin He Abstract Among various biological data, DNA sequence is do ...

individual restriction fragments from mixtures. And most impor- tantly, to do DNA sequencing, at least three steps are needed: c ...

Nowadays, genomic questions are so complex that a depth of information is needed. In ultra-high-throughput sequencing, as many a ...

Table 1Comparison of several high-throughput sequencing methodsMethod Read length Accuracy(single readnot consensus) Reads per r ...

fragments, and to compare the sequence with a reference genome. Also, biologists pay attention to other characteristics of the s ...

When finding a possible spot, compare it with multiple samples. Calculate the mutation rate of your finding, and compare it wit ...

2.2.2 Data Analysis For data analysis, we choose Illumina system as an example. Illu- mina offers a variety of next-generation s ...

haplotype frequencies. Also it can run tests of departure from linkage equilibrium and do thorough analyses of population subdi- ...

The key to data analysis is data mining, of which the basis is sequence similarities. The most common approach to similarity res ...