Science - 16.08.2019
NEUROSCIENCE Bright and photostable chemigenetic indicators for extended in vivo voltage imaging Ahmed S. Abdelfattah^1 , Takash ...
we used a variant of Voltron appended with a 63 – amino acid sequence from the rat potassium channel Kv2.1 that restricts expres ...
Abdelfattahet al.,Science 364 , 699–704 (2019) 16 August 2019 3of6 Fig. 2. Using Voltron to measure mem- brane voltage dynam- ic ...
( 26 ). We extended the imaging period over sev- eral consecutive weeks by injecting additional JF 525 HaloTag ligand beforeeach ...
Abdelfattahet al.,Science 364 , 699–704 (2019) 16 August 2019 5of6 Fig. 4. Voltron reveals millisecond– time scale neural dynami ...
We used Voltron to image zebrafish larvae, which respond to visual input with fast, directed swim bouts that are tailored to the ...
CELL BIOLOGY Active cell migration is critical for steady-state epithelial turnover in the gut Denis Krndija^1 *, Fatima El Marj ...
Krndijaet al.,Science 365 , 705–710 (2019) 16 August 2019 2of6 Fig. 1. Epithelium continues migrating during mitotic block.(A)To ...
Actively migrating cells generate protrusive forces through lamellipodia or filopodia, which are driven by actin polymerization ...
analysis (fig. S6, B and C) confirmed that these protrusions were front-back polarized, analogous to the front-back polarity des ...
Krndijaet al.,Science 365 , 705–710 (2019) 16 August 2019 5of6 Fig. 4. Epithelial cell migration is driven by Arp2/3.(A) EdU pul ...
Arp2/3 knockout (KO) mouse by crossing the Arpc4fl/flmouse ( 30 ) with the Villin:CreERT2 line. Arpc4 depletion (fig. S8A) also ...
new products SCIENCE sciencemag.org/custom-publishing 16 AUGUST 2019 • VOL 365 ISSUE 6454 711 Produced by the Science/AAAS Custo ...
EUROPEAN UNION HORIZON 2020 This project has received funding from the European Union’s Horizon 2020 research and innovation pro ...
The School of Chemistry and Chemical Engineering (SCCE) at Nanjing University (NJU) is amongst the oldest colleges and de- partm ...
online @sciencecareers.org Produced by theScience/AAAS Custom Publishing Ofce. Deliver your message to a global audience of targ ...
To further strengthen our research environment and complement research areas already present at SciLifeLab, we are now looking t ...
Register for a free online account on ScienceCareers.org. Search thousands of job postings and fnd your perfect job. Sign up to ...
University of Missouri DIRECTOR OF BIOLOGICAL SCIENCES The University of Missouri (MU) invites nominations and applications for ...
When I started to work toward my Ph.D. 5 years ago, my mindset was completely different. I believed we are defined by results. S ...
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