Nature - USA (2020-02-13)
corresponding to positions 11−45 of piRNA loci (U[T]:G:C:A = 25.7:23 .4:21.8:29.1)^43. For Fig. 4f, 27-nt genomic sequence pools ...
Article Extended Data Fig. 1 | The current model for the piRNA biogenesis initiated by the piRNA-guided PIWI-catalysed slicing i ...
Extended Data Fig. 2 | Generation and characterization of Trimmer- knockout cells. a, Schematic representation of the domain str ...
Article Extended Data Fig. 3 | BmZuc is required to produce type-E pre-piRNAs for both Siwi and BmAgo3, whereas trailing piRNA p ...
Extended Data Fig. 4 | BmZuc-mediated cleavage of Siwi-loaded pre-pre- piRNAs in vitro. a, Detailed protocol for in vitro recapi ...
Article Extended Data Fig. 5 | See next page for caption. ...
Extended Data Fig. 5 | Calculation of BmZuc scores for Siwi or BmAgo3 based on the randomized sequence library analysis. a, Peak ...
Article Extended Data Fig. 6 | Nucleotide preference around the cleavage site by mouse MitoPLD. a, Peak length distribution of 2 ...
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Nature | Vol 578 | 13 February 2020 | 317 Article Processive extrusion of polypeptide loops by a Hsp100 disaggregase Mario J. Av ...
318 | Nature | Vol 578 | 13 February 2020 Article Different hypothetical translocation models or topologies could be considered ...
Nature | Vol 578 | 13 February 2020 | 319 would yield a continuous series of 2-aa steps, and thus appears incon- sistent with th ...
320 | Nature | Vol 578 | 13 February 2020 Article insert into the ClpB pore and be translocated in a non-loop topology, though w ...
Methods No statistical methods were used to predetermine sample size. The experiments were not randomized. The investigators wer ...
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