Nature - USA (2020-02-13)
Article T.A.), 16H06280, 18H04853 (to K.S.), 19H05795, 19H03394, 16H06280 (to Y. Okada), 18H04751, 19H22520 (to K.M.), JST CREST ...
Extended Data Fig. 1 | See next page for caption. ...
Article Extended Data Fig. 1 | Characterization of the PAS using f luorescence microscopy. a, Measurement of alkaline phophatase ...
Extended Data Fig. 2 | See next page for caption. ...
Article Extended Data Fig. 2 | Characterization of the Atg1-complex droplets in vitro. a, Domain organization of Atg1-complex co ...
Extended Data Fig. 3 | In vitro assay determination of Atg1 and Ptc2 phosphoregulatory activity. a, Purification of TORC1 from y ...
Article Extended Data Fig. 4 | In vitro observation of droplet maturation. Photobleaching experiments were performed for the sca ...
Extended Data Fig. 5 | See next page for caption. ...
Article Extended Data Fig. 5 | Droplets tethered to GUVs via specif ic Atg13–Vac8 interaction retain their liquid-like nature. a ...
Extended Data Fig. 6 | Proposed model of the PAS and its regulation by phosphorylation. Under growing conditions, hyperphosphory ...
1 nature research | reporting summary April 2018 Corresponding author(s): Nobuo N. Noda Reporting Summary Nature Research wishes ...
2 nature research | reporting summary April 2018 Data Policy information about availability of data All manuscripts must include ...
3 nature research | reporting summary April 2018 sigma-aldrich/docs/Sigma/Datasheet/6/a9917dat.pdf; anti-rabbit IgG: https://www ...
306 | Nature | Vol 578 | 13 February 2020 Article Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer ...
Nature | Vol 578 | 13 February 2020 | 307 BD2 of BRD4, respectively). Continued optimization of BD2 selectivity, metabolic stabi ...
308 | Nature | Vol 578 | 13 February 2020 Article prominently downregulated the DHT signature, ABBV-075 induced a broader distri ...
Nature | Vol 578 | 13 February 2020 | 309 Notably, AR acetylation at the K 630 LKK 633 motif that resembles BET bromodomain-bind ...
310 | Nature | Vol 578 | 13 February 2020 Article 60 mg kg−1 (47× the efficacious exposure) did not cause loss of goblet cells o ...
Reporting summary Further information on research design is available in the Nature Research Reporting Summary linked to this pa ...
Article Extended Data Fig. 1 | Characterization of ABBV-744. a, TR-FRET, surface plasmon resonance (SPR) and NanoBRET potency an ...
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