Nature - USA (2020-08-20)

Extended Data Fig. 3 | Flow cytometry gating strategy. a, Forward scatter area (FSC-A) versus forward scatter height (FSC-H) den ...

Article Extended Data Fig. 4 | IFNγ and TNF production prof ile of SARS-CoV-2- specif ic T cells of patients who recovered from ...

Extended Data Fig. 5 | Correlation analysis of SARS-CoV-2-specif ic IFNγ responses with the presence of virus-neutralizing antib ...

Article Extended Data Fig. 6 | Analysis of SARS-CoV N response. PBMCs of patient S-20 were expanded for 10 days and the frequenc ...

Extended Data Fig. 7 | Dominance of SARS-CoV-2 N, NSP7 and NSP13 responses in donors who recovered from COVID-19 or SARS as well ...

Article Extended Data Fig. 8 | Identif ication of SARS-CoV-2 epitopes in donors who were not exposed to SARS-CoV and SARS-CoV-2. ...

Extended Data Fig. 9 | Characterization of SARS-CoV-2 NSP7-specif ic T cell responses in three individuals who were not exposed ...

Article Extended Data Table 1 | Donor characteristics *Disease severity is defined as follows. Mild, with or without chest radio ...

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Nature | Vol 584 | 20 August 2020 | 463 Article Longitudinal analyses reveal immunological misfiring in severe COVID-19 Carolina ...

464 | Nature | Vol 584 | 20 August 2020 Article and IL-22 secreted by ILC3 and TH17 cells, is mounted against fungi and extracel ...

Nature | Vol 584 | 20 August 2020 | 465 in patients with severe disease than in those with moderate disease. By contrast, IL-4 l ...

466 | Nature | Vol 584 | 20 August 2020 Article IL-6, which is linked to CRS, was elevated in patients with severe disease^19. C ...

Nature | Vol 584 | 20 August 2020 | 467 kinetics and magnitudes between patients with severe and moderate disease. Viral load co ...

468 | Nature | Vol 584 | 20 August 2020 Article cluster 3 (Fig. 3c, d). Patients in cluster 3 showed higher expression of marker ...

Nature | Vol 584 | 20 August 2020 | 469 findings were consistent with generalized estimating equations that identified relations ...

Article Methods Ethics statement This study was approved by Yale Human Research Protection Program Institutional Review Boards ( ...

(1:200) (BioLegend), AlexaFluor 647 anti-hIL-4 (8D4-8) (1:100) (BioLeg- end), BB700 anti-hCD183/CXCR3 (1C6/CXCR3) (1:100) (BD Bi ...