Nature - USA (2020-08-20)

3 nature research | reporting summary April 2020 Huh 7.5 (a derivative of Huh 7) was generated in the Laboratory of Virology and ...

Nature | Vol 584 | 20 August 2020 | 443 Article Potently neutralizing and protective human antibodies against SARS-CoV-2 Seth J. ...

444 | Nature | Vol 584 | 20 August 2020 Article blocking the attachment of the virus to host cells. Human antibodies could be us ...

Nature | Vol 584 | 20 August 2020 | 445 plasma from four previously described individuals with recent laboratory-confirmed SARS- ...

446 | Nature | Vol 584 | 20 August 2020 Article chemokine genes—indicative of inflammation—was also reduced in the lungs of each ...

Nature | Vol 584 | 20 August 2020 | 447 Day–6–5 –1^07 Weight measurement Anti-SARS-CoV-2 or isotype control (i.p.) SARS-CoV-2 (i ...

448 | Nature | Vol 584 | 20 August 2020 Article We next tested the protective efficacy of monoclonal antibodies using a recently ...

Nature | Vol 584 | 20 August 2020 | 449 Zhou, P. et al. A pneumonia outbreak associated with a new coronavirus of probable bat ...

Article Methods Data reporting No statistical methods were used to predetermine sample size. The experiments were not randomized ...

S2Pecto–Fab COV2-2165 and SARS-CoV-2 S2Pecto–Fab COV2-2196 com- plexes, the open model of SARS-CoV-2 (PDB: 6VYB) and Fab (PDB: 1 ...

Article mediated by individual monoclonal antibodies at the same total con- centration of antibodies in vitro. To assess whether ...

twofold starting from 1:10 sample dilution, added to the wells (20 μl per well) in triplicate and incubated for 1 h at ambient t ...

Article 6 h before infection, mice were treated with 200 μg of human mono- clonal antibodies via intraperitoneal injection. The ...

B.T.M. performed computational work; J.M., N.L.K., D.H.B., R.S.B., L.B.T., M.S.D., R.H.C. and J.E.C. supervised the research; an ...

Article 01234 0 25 50 75 100 Log 10 [m Ab](ng/m l) %R elativeIn fe c tion COV2-2813 COV2-2819 COV2-2828 COV2-2832 COV2-2835 COV2 ...

(^0) -1 01234 25 50 75 100 mAbconcentration (ng/mL) O.D. 450 nm (^0) -1 0123 4 25 50 75 100 mAbconcentration (ng/mL) O.D.450 nm ...

Article (^0) -2 -1 0123 1 2 3 4 (^0) -2 -1 0123 1 2 3 4 (^0) -2 -1 0123 1 2 3 4 (^0) -2 -1 0123 1 2 3 4 (^0) -2 -1 0 123 1 2 3 4 ...

0 10 20 30 40 100 mAbconcentration(ng/mL) O. D. 4 5 0n m b % mAb binding inhibition mAbconcentration(ng/mL) O. D. 450 nm Serum o ...

Article wt K378AK386AD389AN439AK444AG447RV483AF486AN487AQ493AS494AP499RT500RN501AY505A 0.0 0.2 0.4 0.6 0.8 1.0 1.2 1.4 COV2-209 ...

Extended Data Fig. 6 | Sequence features of the human monoclonal antibodies used in animal studies and monoclonal antibody pharm ...