Nature - USA (2020-10-15)

Article Extended Data Fig. 7 | Somatostatin-specif ic reduction of p-eIF2α facilitates L-LTP. a, b, Immunof luorescent labelling ...

Extended Data Fig. 8 | Eif2a cKIPvalb mice show no change in consolidation of contextual and auditory fear memory. a, Diagram de ...

Article Extended Data Fig. 9 | No change in L-LTP threshold in Eif2a cKIPvalb mice. a–c, A 1 × HFS induced short-lasting E-LTP i ...

Extended Data Fig. 10 | TBS-induced LTP in CA1 oriens/alveus (O/A) somatostatin-expressing interneurons exerts a more robust sup ...

1 nature research | reporting summary October 2018 Corresponding author(s): Nahum Sonenberg, Kobi Rosenblum and Vijendra Sharma ...

2 nature research | reporting summary October 2018 Field-specific reporting Please select the one below that is the best fit for ...

3 nature research | reporting summary October 2018 Animals and other organisms Policy information about studies involving animal ...

Nature | Vol 586 | 15 October 2020 | 417 Article Negative feedback control of neuronal activity by microglia Ana Badimon1,2,3, H ...

418 | Nature | Vol 586 | 15 October 2020 Article We found that the microglial response to neuronal activation is asso- ciated wi ...

Nature | Vol 586 | 15 October 2020 | 419 phenotypes (Extended Data Fig. 5j–l) in the striatum, and the abnormal hyper-responsive ...

420 | Nature | Vol 586 | 15 October 2020 Article addition, we found that microglia determine the threshold for stri- atal neuron ...

Nature | Vol 586 | 15 October 2020 | 421 absence of strong neuronal activation, microglial motility is character- ized by the co ...

422 | Nature | Vol 586 | 15 October 2020 Article manner (Fig. 3h). The pharmacological inhibition of microglial ATP/ ADP-sensing ...

Nature | Vol 586 | 15 October 2020 | 423 environment to neurons and thereby to direct specific behavioural responses. Microglia ...

Article Methods Animals Mice were housed two to five animals per cage with a 12-h light–dark cycle (lights on from 0700 to 1900  ...

cocktail (Roche), 10 μl/ml RNasin (Promega) and Superasin (Applied Biosystems)). Homogenates were centrifuged for 10 min at 2,00 ...

Article zero UMIs in grey. Cluster-specific upregulated genes (P < 0.05) were determined using the ‘Significant genes’ tool i ...

2-μm intervals, with a 40×/1.3 oil objective at 0.6 or 1× zoom. For single plane images, 4.6-μm images were acquired with 20×/0. ...

Article PEI (P3143, Sigma) in borate buffer (boric acid (A73-500, Fisher), sodium tetraborate (221732, Sigma)). After incubation ...

The motion-corrected data were later run through a pipeline adapted from Suite2P (https://github.com/cortex-lab/Suite2P)^78 for ...