Nature - USA (2020-09-24)

Article Extended Data Fig. 1 | Erythrocytic cycle of malaria parasites. Illustration of the erythrocytic (RBC) stage of the mala ...

Extended Data Fig. 2 | See next page for caption. ...

Article Extended Data Fig. 2 | Invasion process across Dantu genotype groups studied by time-lapse video microscopy. a, The forc ...

Extended Data Fig. 3 | Distribution of reticulocytes and RNA concentrations across Dantu genotypes. Reticulocyte counts, and con ...

Article Extended Data Fig. 4 | Plasma membrane prof iling by tandem mass tag (TMT)-based MS3 mass spectrometry. The impact of th ...

Extended Data Fig. 5 | Representative membrane f luctuation spectra for non-Dantu, Dantu-heterozygous and Dantu-homozygous RBCs. ...

Article Extended Data Fig. 6 | Relationship between biophysical properties in non-Dantu and Dantu-homozygote RBCs. a, Scatter pl ...

Extended Data Fig. 7 | Reduction of membrane tension in non-Dantu and Dantu-homozygous RBCs on treatment with phloretin. a–d, Bi ...

Article Extended Data Fig. 8 | Comparing parasite invasion and biomechanical properties of frozen and fresh RBCs. a, The invasio ...

Extended Data Fig. 9 | Decoupling tension and bending modulus with flickering analysis. To test our ability to decouple tension ...

Article Extended Data Fig. 10 | Membrane f lickering spectroscopy amplitude analysis. a, To justify our choice of modes for fitt ...

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584 | Nature | Vol 585 | 24 September 2020 Article Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates Pau ...

Nature | Vol 585 | 24 September 2020 | 585 (IC 50 ) values of 2.2 μM (0.7 μg ml−1) and 4.4 μM (1.4 μg ml−1) at 48 and 72 h after ...

586 | Nature | Vol 585 | 24 September 2020 Article exposure (Hi D1 + AZTH, n = 5). No effects of treatment were observed on eith ...

Nature | Vol 585 | 24 September 2020 | 587 Pathogenesis and host response to HCQ treatment High alanine aminotransferase and cre ...

Article Methods Ethics and biosafety statement Cynomolgus macaques (M. fascicularis), aged 37–40 months and origi- nating from M ...