BIOINORGANIC CHEMISTRY A Short Course Second Edition

20 INORGANIC CHEMISTRY ESSENTIALS Structure – activity relationship studies have shown that the complex forms stable adducts wit ...

Many organometallic complexes are clusters involving multiple metals that feature metal – metal bonds. The electrons in Me – Me ...

22 INORGANIC CHEMISTRY ESSENTIALS do not indicate Fe – Fe bonds. It is known that for the Fe 4 S 4 cubane found in biological sy ...

tary when there are equal numbers of oxidants and reductants and the metals transfer equal numbers of electrons as shown in equa ...

24 INORGANIC CHEMISTRY ESSENTIALS 2RSH RSSR− → −−− (1.30) The second type of biological electron transfer involves a variety of ...

1 2 ONADHH HONAD 22 ++→+++ (1.31) The simplest electron transfer reactions are outer sphere. The Franck – Condon principle state ...

26 INORGANIC CHEMISTRY ESSENTIALS It is beyond the scope of this text to continue the discussion of Marcus theory. Qualitatively ...

inorganic and bioinorganic chemistry texts referenced earlier in this chapter and here are good sources for answering the additi ...

28 INORGANIC CHEMISTRY ESSENTIALS Gray , H. B. ; Ellis , W. R. , in Bertini , I. ; Gray , H. B. ; Lippard , S. J. ; Valentine , ...

29 2 Bioinorganic Chemistry: A Short Course, Second Edition, by Rosette M. Roat-Malone Copyright © 2007 John Wiley & Sons, I ...

30 BIOCHEMISTRY FUNDAMENTALS biochemical reactions, or structural materials in muscles and tendons, or small molecule carriers s ...

PROTEINS 31 Figure 2.1 Zwitterions of nonpolar hydrophobic amino acids at physiological pH. +H 3 NC H H COO- +H 3 NC H CH 3 COO- ...

32 BIOCHEMISTRY FUNDAMENTALS amino acids are shown in their zwitterion form at pH 7 in which they have their COOH group (p Ka = ...

PROTEINS 33 different metal ions (Asp - M 1 M 2 ). Some examples are shown in Figure 2.5 , but it should be remembered that thes ...

34 BIOCHEMISTRY FUNDAMENTALS secondary, tertiary, and quaternary structure of proteins controls their three - dimensional shape, ...

PROTEINS 35 Figure 2.7 A peptide of four amino acids. NH CH C CH 2 OH O SH H 2 NCH C CH 3 O HN CH C HC 2 HC 2 O CH 2 CH 2 NH C N ...

36 BIOCHEMISTRY FUNDAMENTALS Figure 2.9 Protein secondary structures (many R groups omitted for clarity). (Adapted with permissi ...

PROTEINS 37 The tertiary structure of proteins arises from the interactions of the various R groups along the polypeptide chain. ...

38 BIOCHEMISTRY FUNDAMENTALS bacterial infection by breaking the tough skin of carbohydrate chains, inter- locked by short pepti ...

PROTEINS 39 though much is known. Predicting protein folding is an enormous challenge. Most proteins contain dozens or hundreds ...