Organic Chemistry

O 2 cytochrome P 450 a diol epoxide O O H 2 O epoxide hydrolase HO HO HO HO Section 12.8 Arene Oxides 461 BENZO[a]PYRENE AND CAN ...

462 CHAPTER 12 Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds 3-D Molecules: [15]-Crown-5; [12]-Crown- ...

Section 12.9 Crown Ethers 463 3-D Molecule: [18]-Crown-6 with potassium ion Donald J. Cram (1919–2001)was born in Vermont. He re ...

464 CHAPTER 12 Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds protic polar solvent (Section 10.3). Rec ...

Section 12.10 Thiols, Sulfides, and Sulfonium Salts 465 The blistering caused by mustard gas is due to the high local concentrat ...

466 CHAPTER 12 Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds PROBLEM 27 Finding that mustard gas inte ...

Section 12.11 Organometallic Compounds 467 Table 12.3 The Electronegativities of Some of the Elementsa aFrom the scale devised b ...

Reaction with the metal converts the alkyl halide into a compound that will react with electrophiles instead of nucleophiles. Th ...

This means that Grignard reagents and organolithium compounds cannot be prepared from compounds that contain acidic groups or gr ...

470 CHAPTER 12 Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds polar. (The carbon–magnesium bond is abo ...

prepare the following compounds because vinyl and aryl halides cannot undergo nucleophilic attack (Section 10.8): Gilman reagent ...

472 CHAPTER 12 Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds The Heck reactioncouples an aryl, benzyl ...

PROBLEM 36 The organoborane used in a Suzuki reaction is prepared by the reaction of catecholborane with an alkene or an alkyne ...

474 CHAPTER 12 Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds from compounds that contain acidic group ...

Summary of Reactions 475 Ring-opening reactions of epoxides(Section 12.7) Reactions of arene oxides: ring opening and rearrange ...

476 CHAPTER 12 Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds Reaction of an aryl,benzyl, or vinyl ha ...

Problems 477 Indicate which alcohol will undergo dehydration more rapidly when heated with a. d. b. e. c. f. Which of the fol ...

478 CHAPTER 12 Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds Propose a mechanism for the following r ...

Problems 479 Give the major product expected from the reaction of 2-ethyloxirane with each of the following reagents: a. 0.1 M ...

480 CHAPTER 12 Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds One method used to synthesize an epoxid ...