Organic Chemistry

Section 11.7 A Kinetic Isotope Effect 421 11.7 A Kinetic Isotope Effect A mechanismis a model that accounts for all the experime ...

422 CHAPTER 11 Elimination Reactions of Alkyl Halides • Competition Between Substitution and Elimination Table 11.5 Relative Rea ...

Section 11.8 Competition Between Substitution and Elimination 423 A bulky base encourages elimination over substitution. A weak ...

424 CHAPTER 11 Elimination Reactions of Alkyl Halides • Competition Between Substitution and Elimination Table 11.6 Summary of t ...

Section 11.9 Substitution and Elimination Reactions in Synthesis 425 PROBLEM 19 Indicate whether the alkyl halides listed will ...

less hindered alkyl group should be provided by the alkyl halide and the more hin- dered alkyl group should come from the alkoxi ...

To synthesize 2-methyl-2-butene from 2-bromo-2-methylbutane, you would use conditions (a high concentration of in an aprotic pol ...

428 CHAPTER 11 Elimination Reactions of Alkyl Halides • Competition Between Substitution and Elimination The vinylic halide inte ...

Section 11.12 Designing a Synthesis II: Approaching the Problem 429 Three- and four-membered rings are strained, so they are les ...

430 CHAPTER 11 Elimination Reactions of Alkyl Halides • Competition Between Substitution and Elimination Example 1.How could you ...

Section 11.12 Designing a Synthesis II: Approaching the Problem 431 Now the reaction sequence can be written in the forward dire ...

432 CHAPTER 11 Elimination Reactions of Alkyl Halides • Competition Between Substitution and Elimination PROBLEM 28 Design a mul ...

Key Terms 433 the conditions favor or reactions. When reactions are favored, primary alkyl halides form primarily substitution p ...

434 CHAPTER 11 Elimination Reactions of Alkyl Halides • Competition Between Substitution and Elimination Problems Give the majo ...

Problems 435 Rank the following compounds in order of decreasing reactivity in an E2 reaction: Using the given starting materia ...

436 CHAPTER 11 Elimination Reactions of Alkyl Halides • Competition Between Substitution and Elimination For each of the follow ...

I n Chapters 10 and 11, we saw that alkyl halides undergo substitution and elimina- tion reactions because of their electron- wi ...

438 CHAPTER 12 Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds convert an OH group into a weaker base i ...

Section 12.1 Substitution Reactions of Alcohols 439 Secondary and tertiary alcohols undergo SN 1 reactions with hydrogen halides ...

440 CHAPTER 12 Reactions of Alcohols, Ethers, Epoxides, and Sulfur-Containing Compounds Howard J. Lucas (1885–1963) was born in ...