Stem Cell Microenvironments and Beyond

72 Acknowledgments This work was partly supported by grant FCE 103356 from ANII and grant 167 from Wings for Life Spinal Cord Re ...

73 Corns LF, Deuchars J, Deuchars SA (2013) GABAergic responses of mammalian ependymal cells in the central canal neurogenic nic ...

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75 Kutna V, Sevc J, Gombalov Z, Matiasova A, Daxnerova Z (2014) Enigmatic cerebrospinal fluid- contacting neurons arise even aft ...

76 Marzesco AM, Janich P, Wilsch-Bräuninger M, Dubreuil V, Langenfeld K, Corbeil D, Huttner WB (2005) Release of extracellular m ...

77 Piatt J, Piatt M (1958) Transection of the spinal cord in the adult frog. Anat Rec 131:81–95 Pinto L, Götz M (2007) Radial gl ...

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79 Wang DD, Kriegstein AR (2009) Defining the role of GABA in cortical development. J Physiol 587:1873–1879 Wang X, Arcuino G, T ...

© Springer International Publishing AG 2017 81 A. Birbrair (ed.), Stem Cell Microenvironments and Beyond, Advances in Experiment ...

82 Keywords Neural stem cell • Development • Evolution • Extracellular matrix Vasculature • Cancer 6.1 Intrinsic vs. Extrinsic ...

83 guanosine triphosphatase–activating protein (called ARHGAP11B) has been sin- gled out as a gene expressed only in human RGCs ...

84 Fig. 6.1 (a) NSCs isolated from the embryonic cortex at E12.5 and kept in culture exhibit the characteristic structure of NEP ...

85 6.2 The NSC Microenvironment During Embryogenesis As already mentioned NSCs operate in microenvironments with limited presenc ...

86 in collagen IV, nidogen, perlecan and fibronectin (Akita et  al. 2008 ; Fietz et  al. 2012 ; Garcion et al. 2004 ; Lathia et  ...

87 has been produced, RGCs receive feedback instructing them to switch towards glio- genesis; cardiotrophin-1 produced by neuron ...

88 is not expressed in the SVZ parenchyma (Garcion et  al. 2004 ), re-appears in the human SVZ, both in the basal progenitor and ...

89 BVs (Tan et al. 2016 ). Notably, this cell-to-cell communication is mediated by inte- grin/laminin interactions, as has been ...

90 6.3 The NSC Microenvironment of the Postnatal CNS Contrary to the assumption that neurogenesis in mammals is completed by the ...

91 2008 ; Tavazoie et al. 2008 ). We have suggested that ependymal cells are an impor- tant component of the niche, since their ...

92 6.3.1.4 Cell-ECM Interactions NSCs express low levels of ECM receptors such as integrin-α 6 β1, syndecan-1 and Lutheran, but ...