Stem Cell Microenvironments and Beyond

93 Patched it led to a transient increase in proliferation followed by exhaustion of type B1 cells (Daynac et al. 2016 ). Shh si ...

94 and Notch signaling was also shown to regulate quiescence of NSCs at the cell contact between NSCs and endothelial cells, med ...

95 et al. 2014 ). Recently, cholinergic stimulation was shown to control the response of SEZ cells to experimental stroke (Wang ...

96 astrocyte neural stem cell transit amplifying precursor granule neuron blood vessell neuroblast c abSEZ SGZ ependymal cell Fi ...

97 6.3.2.1 Cell-Cell and Cell-ECM Contact The ECM composition of the SGZ has not been thoroughly investigated so far. In vitro a ...

98 et  al. ( 2016 )). Nevertheless, it is still early days and no solid hypotheses can be formed. Many factors such as BDNF and ...

99 hippocampus, exerts a mitogenic effect in cultured hippocampal NSCs. This is due to the enhanced progression from G1 to S pha ...

100 change (Kerever et al. 2015 ): their numbers are decreased but their size increases and their composition in heparan sulfate ...

101 also been implicated in the promotion of glioma invasion properties through the expression of integrin α3 (overexpressed in ...

102 6.4.2.2 CSCs-Vasculature Interactions Extensive interplay between CSCs and endothelial cells (ECs) has been identified, one ...

103 miR-145 (negative regulator), which is downregulated in CSCs (Alvarado et  al. 2016 ). High JAM-A/low miR-145 expression sig ...

104 6.4.3 Other Brain Cancer Types Ependymoma and medulloblastoma CSCs interact with ECs in matrigel cultures and promote EC net ...

105 Alvarez-Buylla A, García-Verdugo JM, Tramontin AD (2001) A unified hypothesis on the lineage of neural stem cells. Nat Rev N ...

106 Borrell V, Calegari F (2014) Mechanisms of brain evolution: regulation of neural progenitor cell diversity and cell cycle le ...

107 Culver JC, Vadakkan TJ, Dickinson ME (2013) A specialized microvascular domain in the mouse neural stem cell niche. PLoS One ...

108 progenitor self-renewal. Proc Natl Acad Sci U S A 109:11836–11841. https://doi.org/10.1073/ pnas.1209647109 Florio M, Albert ...

109 Hartenstein V, Wodarz A. (2013) Initial neurogenesis in Drosophila. Wiley Interdiscip Rev Dev Biol 2:701–721. doi: 10.1002/w ...

110 Javaherian A, Kriegstein A (2009) A stem cell niche for intermediate progenitor cells of the embry- onic cortex. Cereb Corte ...

111 Kim Y, Wang W-Z, Comte I, Pastrana E, Tran PB, Brown J et al (2010) Dopamine stimulation of postnatal murine subventricular ...

112 Li G, Fang L, Fernández G, Pleasure SJ (2013) The ventral hippocampus is the embryonic origin for adult neural stem cells in ...