Organ Regeneration Based on Developmental Biology

Takashi Tsuji Editor Organ Regeneration Based on Developmental Biology ...

Organ Regeneration Based on Developmental Biology ...

Takashi Tsuji Editor Organ Regeneration Based on Developmental Biology ...

ISBN 978-981-10-3766-5 ISBN 978-981-10-3768-9 (eBook) DOI 10.1007/978-981-10-3768- Library of Congress Control Number: 201793557 ...

This book is dedicated to the memory of Yoshiki Sasai, a scientist who made a great contribution to the advancement of developme ...

vii Preface Organogenesis, the generation of functional tissues and organs following an estab- lished body plan during developme ...

viii niches. These studies provide a better understanding of organogenesis in develop- mental biology and represent a breakthrou ...

ix Contents 1 Telencephalic Tissue Formation in 3D Stem Cell Culture .................. 1 Taisuke Kadoshima, Hideya Sakaguchi, a ...

x 11 Recapitulating Development to Generate Kidney Organoid Cultures ........................................................... ...

xi List of Contributors Mototsugu  Eiraku RIKEN Center for Developmental Biology, Kobe, Hyogo, Japan Alhasan  N.  Elghouche Depa ...

xii Ryuichi  Nishinakamura Department of Kidney Development, Institute of Molecular Embryology and Genetics, Kumamoto University ...

xiii Koh-ei Toyoshima Department Regenerative Medicine, Plastic and Reconstructive Surgery, Kitasato University School of Medici ...

© Springer Nature Singapore Pte Ltd. 2017 1 T. Tsuji (ed.), Organ Regeneration Based on Developmental Biology, DOI 10.1007/978-9 ...

2 1.1 Introduction The brain is the most complex organ in the human body. It has increased in size and complexity throughout hum ...

3 induced pluripotent stem (iPS) cells), which can recapitulate complex organ struc- tures, offer us a new opportunity to unders ...

4 1.2 The Cerebral Cortex 1.2.1 Development of the Cerebral Cortex In Vivo Among the various telencephalic regions, the cerebral ...

5 SVZ: the primate (especially human) cortex is characterized by a highly expanded SVZ, which is subdivided into inner and outer ...

6 1.2.2 3D Cortical Tissue Generation In Vitro Using SFEBq methods, mouse ESC-derived aggregates can be differentiated into cort ...

7 difference in developmental speed in vivo. Indeed, the emergence of each subtype of cortical pyramidal neuron in vitro substan ...

8 telencephalic neuroepithelium (Foxg1+) A B apical apical Cajal–Retzius cell zones: Reelin + CP: Tbr1 + SVZ: Tbr2 + VZ: Pax6 + ...