Catalyzing Inquiry at the Interface of Computing and Biology
COMPUTATIONAL MODELING AND SIMULATION AS ENABLERS FOR BIOLOGICAL DISCOVERY 119 necessary to create a number of more refined mode ...
120 CATALYZING INQUIRY more compelling and more accessible interpretations of what the models predict.^3 This has made it easier ...
COMPUTATIONAL MODELING AND SIMULATION AS ENABLERS FOR BIOLOGICAL DISCOVERY 121 exponential growth (if birth rates exceed mortali ...
122 CATALYZING INQUIRY resource limitations on stabilizing a population that would otherwise grow explosively. All of these conc ...
COMPUTATIONAL MODELING AND SIMULATION AS ENABLERS FOR BIOLOGICAL DISCOVERY 123 give a framework for observations (as noted in Se ...
124 CATALYZING INQUIRY 5.2.10 Models Can Link What Is Known to What Is Yet Unknown, In the words of Pollard, “Any cellular proce ...
COMPUTATIONAL MODELING AND SIMULATION AS ENABLERS FOR BIOLOGICAL DISCOVERY 125 Lander explains the intellectual paradigm for det ...
126 CATALYZING INQUIRY other hand, statistical influence models are not causal and may not lead to a better understanding of und ...
COMPUTATIONAL MODELING AND SIMULATION AS ENABLERS FOR BIOLOGICAL DISCOVERY 127 human intuition about complex nonlinear systems i ...
128 CATALYZING INQUIRY relates to more realistic situations. In this case, simulation takes over where analysis ends.^26 Some sy ...
COMPUTATIONAL MODELING AND SIMULATION AS ENABLERS FOR BIOLOGICAL DISCOVERY 129 recognizing that what is “essential” cannot be de ...
130 CATALYZING INQUIRY concentration would have to be modeled discretely. As more of it is synthesized, the concentration become ...
COMPUTATIONAL MODELING AND SIMULATION AS ENABLERS FOR BIOLOGICAL DISCOVERY 131 5.3.4 Model Comparison and Evaluation, Models are ...
132 CATALYZING INQUIRY time scale). In some cases, leaving out some of the interacting components (e.g., those whose interaction ...
COMPUTATIONAL MODELING AND SIMULATION AS ENABLERS FOR BIOLOGICAL DISCOVERY 133 Box 5.4 Formal Modeling of Caenorhabditis elegans ...
134 CATALYZING INQUIRY 5.4.2.1 Cellular Modeling and Simulation Efforts, The preceding discussion has been highly abstract. This ...
COMPUTATIONAL MODELING AND SIMULATION AS ENABLERS FOR BIOLOGICAL DISCOVERY 135 to that component, and (3) creating classificatio ...
136 CATALYZING INQUIRY 5.4.1.3 Molecular Docking, Using a simple, uniform representation of molecular surfaces that requires min ...
COMPUTATIONAL MODELING AND SIMULATION AS ENABLERS FOR BIOLOGICAL DISCOVERY 137 cally pooling relevant data. The expected surfeit ...
138 CATALYZING INQUIRY Calcium Model VOLUME 012345 ATOM-NAME-IS-ANY < > > > ATOM-NAME-IS-C < < > > > ...
«
3
4
5
6
7
8
9
10
11
12
»
Free download pdf