Science - USA (2022-04-29)

( 1 ). For example, TADs are thought to regulate gene expression by increasing the frequency of enhancer-promoter interactions w ...

conditions ( 14 ), we could trackFbn2looping dynamics at 20-s resolution for >2 hours (Fig. 1D and movies S1 to S4). After DN ...

analysis showed a loss of chromatin binding (fig. S7). For WAPL, depletion took 4 hours and was less complete (fig. S5), long-te ...

Because of localization noise and substantial temporal correlations in the data, simple analysis methods failed when benchmarked ...

speed). When cohesin reaches a CTCF site, it has a 12.5% probability of stalling, which, using the estimate of 50% CTCF occupanc ...

HYDROGELS Piezoionic mechanoreceptors: Force-induced current generation in hydrogels Yuta Dobashi1,2,3, Dickson Yao^1 , Yael Pet ...

function of deformation, as discussed in the supplementary materials. The streaming potentials that generate the responses plott ...

andsolvent.Thisisobservedintheioniccon- ductivity, for which that of the polymer gel is higher than that of the bulk electrolyte ...

the pores. Nonetheless, the derived expres- sion for piezoionic coefficient provides useful predictions regarding the effects of ...

receptor deformation upon a given pertur- bation ( 28 , 29 ), whereas piezoionic current spikes are modified by permeability, mo ...

(Fig. 3B). The pressure sensitivity of a single mechanoreceptor unit is 8mV/kPa (a=8× 10 −^9 V/Pa), probed with pressures of up ...

NEUROETHOLOGY Food wanting is mediated by transient activation of dopaminergic signaling in the honey bee brain Jingnan Huang^1 ...

captured upon their first active visit (i.e., they flew on their own rather than being trans- ported by the experimenter) to a f ...

needs also activate a dopamine wanting sys- tem. To this end, we studied whether starva- tion of individual foragers enhanced do ...

significantly between treatments (Fig. 3C;H3,194= 17.47,P< 0.0001). Bees with elevated dopa- mine levels learned better than ...

individuals with a sophisticated division of labor ( 20 ). As a result, their wanting sys- tem integrates both the social and th ...

linked to plausible progenitors, indicating that contact tracing detected most cases. Further analysis indicated that 83 to 95% ...

by these introductions, to the spatially resolved case and dog density data to investigate the processes that modulate transmiss ...

dogs on the landscape (Fig. 4). There remains ambiguity in the mechanisms that underpin density-independent transmission at high ...

such as host density, but are poorly under- stood. Behavioral manifestations of infection that depend on sociological and pathol ...