A Guidebook to Mechanism in Organic Chemistry
Electrophilic and Nucleophilic Substitution in Aromatic Systems p. 88) before it reacts with benzene. In the presence of FeCI 3 ...
Friedel-Crafts Reaction The main drawback in the preparative use of the Friedel-Crafts reaction is polyalkylation, however (p. 1 ...
Electrophilic and Nucleophilic Substitution in Aromatic Systems Me,C -£o=o C 11^ CO+Me,C PhCMe, A useful synthetic application o ...
Diazo Coupling Thus the 2,4-dinitrophenyldiazonium cation will couple with Ph-OMe and the 2,4,6-compound with the hydrocarbon me ...
Electrophilic and Nucleophilic Substitution in Aromatic Systems " With most primary amines this is virtually the sole product, w ...
Diazo Coupling products derivable from amines, this latter difference is much less marked. The formation of diazoamino compounds ...
0 Electrophilic and Nucleophilic Substitution in Aromatic Systems which shows all the characteristics (in the way of effect of s ...
The Effect of a Substituent already Present But this is not the only way in which a substituent can affect electron- availabilit ...
Electrophilic and Nucleophilic Substitution in Aromatic Systems * and it is not possible to say, a priori, whether the overall e ...
The Effect of a Substituted already Present Direction in Y OH 1-6 NH, 1-5 OMe 1-2 *-+ Me 0-3 H 00 ci 1-6 CHO 2-8 +-*• SO,H 3-8 N ...
Electrophilic and Nucleophilic Substitution in Aromatic Systems * clearly OMe, being an electron-donating group, is able to stab ...
The Position of Substitution NO, (XVII) (XVIIa) (XVII6) NO, 'NO, © NO, (XVIII) (XVIIIa) (XVIII6) 0,N H 0 2 N H ^ (XlXa) "* (XIX« ...
Electrophilic and Nucleophilic Substitution in Aromatic Systems * MeOx MeO® MeO® 0 e OMe activating thtfo- and /^-positions pref ...
The Position of Substitution In practice, however, it substitutes ojp- (it also undergoes substitution on the CH 2 of the vinyl ...
Electrophilic and Nucleophilic Substitution in Aromatic Systems * (XXI) Conversely aniline, normally o/p-directing, becomes in p ...
Ortho/Para Ratios nitrating mixture is due to the small, residual concentration of free aniline, a very weak base (cf. p. 52), t ...
Electrophilic and Nucleophilic Substitution in Aromatic Systems Group introduced Cl NO, Br SOsH Percentage o-^39 30 11 % Percent ...
Electrophilic Substitution of Other Aromatic Species (XXII) That is o- and p- to the activating substituent, Me, but not m- to t ...
Electrophilic and Nucleophilic Substitution in Aromatic Systems More forms can also be written in each case in which the positiv ...
Electrophilic Substitution of Other Aromatic Species atom because of the latter's being more electronegative than carbon. This i ...
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