A Guidebook to Mechanism in Organic Chemistry
Addition to Carbon-Carbon Double Bonds Thus conjugated dienes are reduced to dihydro-derivatives by sodium and alcohol whereas n ...
Diels-Alder Reaction CHa=CH—CH=CHa • CHa—CH—CH=CH, (XXXIII) CHa—CH-^CH=^CHa H X CH,—CH=CH—CHa H (XXXIV) H Br I CHa—CH—CH=CH 2 (X ...
Addition to Carbon-Carbon Double Bonds i.e. l:4-addition, proceeding cis, via a cyclic transition state (cf. the pyrolysis of es ...
Addition of Anions ADDITION OF ANIONS As has already been seen (p. 130) the introduction of electron-with drawing groups into a ...
Addition to Carbon-Carbon Double Bonds KTO© R.CHC1IO >- R..C Clio > RjCCHO C1I. 0:11—C^N CH 2 —CH^ci-N T R„CCHO CH 2 CH 2 ...
Addition to «&-Unsaturated Carbonyl Compounds With more pronouncedly nucleophilic reagents, e.g. Grignard reagents, eCN, etc ...
Addition to Carbon-Carbon Double Bonds (XLII) Me.C x5 \ CH COjEt EOEI | CH,(CO,Et), > CO,Et (XLIII) CH, O^0 / CH=C / \ Me,C C ...
Addition to afi-Unsaturated Carbonyl Compounds The compound does in fact exist virtually entirely in the enol form: O / CH,,—C / ...
7 ADDITION TO GARBON-OXYGEN DOUBLE BONDS THE structure of the carbonyl group in aldehydes and ketones is, to judge from its reac ...
Structure and Reactivity similar situation obtains for any quantity of acid will convert it to the ® unreactive species, R-NHa. ...
Addition to Carbon-Oxygen Double Bonds « ^)J-H etc. Thus benzaldehyde is less reactive than aliphatic aldehydes. This effect is ...
Hydration Thus it has been shown that the percentage hydration at 20° of formaldehyde, acetaldehyde and acetone is 99-99, 58. an ...
Addition to Carbon-Oxygen Double Bonds Of H—C-e-C—H H,0 O OH II I H—C—C—H AH CI OH I I Cl—C—C—H A OH o (III) (IV) (IV) is ninhyd ...
Addition of Thiols An ^ with the hemi-acetal is often set up on dissolving the aldehyde in the alcohol but conversion to the ace ...
Addition to Carbon-Oxygen Double Bonds The addition of HCN is base-catalysed indicating that the rate-deter mining step of the ...
Hydride Ion Reactions HO HsO HO R—N: • C > R—N—C > R—N—C— I FAST H H HA (V) R—N=C<^+H.O «-^» (VI) dehydration of the la ...
Addition to Carbon-Oxygen Double Bonds * With esters, the initial reaction is a nucleophilic displacement, fol lowed by reducti ...
Cannizzaro Reaction Hydride ion, He, is transferred from aluminium isopropoxide to the ketone (VIII) via a cyclic transition sta ...
Addition to Carbon-Oxygen Double Bonds charge. That the migrating hydride ion is transferred directly from one molecule of aldeh ...
Reactions with Metals form a carbon-carbon bond yielding the magnesium salt (XIV) of a pinacol; subsequent acidification yields ...
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