ECMO-/ECLS
The anemia of prematurity is a normocytic, normochromic anemia that is characterized by inadequate production of erythropoietin. ...
Hematocrit of > 35% IV. Transfusion in the PICU A study of over 1000 admissions to the PICU showed that the four significan ...
arm). This study added support to the theory that children will tolerate a more restrictive transfusion threshold without an inc ...
Premature infants are at an increased risk of intraventricular hemorrhage. Underdeveloped subependymal matrix and diminished coa ...
VI. Transfusion Reactions There are several types of tranfusion reactions (see Table 2). When a transfusion reaction is suspecte ...
lung injury (TRALI) has now become the leading cause of transfusion-related morbidity and mortality worldwide. Defined criteria ...
TABLE: TYPES OF TRANSFUSION REACTIONS TYPE OF TRANSFUSION REACTION CAUSE SYMPTOMS TREATMENT Hemolytic, immediate ABO incompatibi ...
migrates to recipient’slungs. Donor antibodies reacting with recipient antigen on granulocytes. Sicker patients tend to be more ...
of venous catheter devices, mechanical ventilation, malignancy, prolonged stay in the hospital (> 5 days). Additionally, incr ...
needed, heparin reversal can be reversed with protamine (1 mg protamine for 100 units of heparin). Low molecular weight heparin ...
Hebert PC, Wells G, Blajchman MA, et al. A Multicenter, Randomized, Controlled, Clinical Trial of Transfusion Requirements in ...
Bateman ST, Lacroix J, Boven K, et al. Anemia, blood loss, and blood transfusions in North American children in the intensive c ...
Beardsley DS. Venous thromboembolism in the neonatal period. Semin Perinatal 2007;31:250 - 53. ...
Chapter 12 SEDATION AND ANALGESIA Jill Zalieckas, MD Christopher Weldon, MD, PhD.^ (^) I. Introduction The alleviation of pain a ...
sedation (conscious sedation/sedation/analgesia), is a drug-induced depression of consciousness during which patients are able t ...
infants and children [9]. Payen et al also found continuous intravenous sedation was an independent risk factor for prolonged me ...
Elimination half life is prolonged in neonates due to reduced hepatic activity and blood flow [2,13,14](Table 1) Morphine [5,13 ...
Clinical characteristics: 100 times more potent than morphine. most hemodynamically stable opioid Dosing: 1 mcg/kg o sufenta ...
Onset & elimination: slow elimination, long duration of action; half life 19 hours Metabolism: hepatic metabolism. metab ...
Meperidine [13]^ Metabolized into normeperidine, which is toxic metabolite that can accumulate in patients with liver disease ...
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