Stem Cell Microenvironments and Beyond

© Springer International Publishing AG 2017 235 A. Birbrair (ed.), Stem Cell Microenvironments and Beyond, Advances in Experimen ...

236 12.1 Introduction Regenerative medicine is defined as a branch of translational research that congre- gates important areas ...

237 The role of ECM deserves special attention since in one hand, the interactions of the cells with the ECM provide essential m ...

238 However, in recent years promising studies have been done on yolk sac mesen- chymal SC not only for human (Wang et al. 2008 ...

239 high renewal capacity, expression of embryonic markers, multipotency to differenti- ate in different cell lines, low immunog ...

240 can be associated with the histological and physiological characteristics regarding to the microenvironment associated in th ...

2 41 References Antonucci I, Pantalone A, Tete S, Salini V, Borlongan CV, Hess D, Stuppia L (2012) Amniotic fluid stem cells: a ...

242 Fratini P, Carreira AC, Alcântara D, de Oliveira e Silva FM, Rodrigues MN, Miglino MA (2016) Endothelial differentiation of ...

243 Mossman HW (1987) Vertebrate fetal membranes: comparative ontogeny and morphology: evo- lution; phylogenetic significance: b ...

244 Xiao-dong N, Mei-ling Z, Zi-ping Z, Wei-hua Y, Xiu-ming Z, Peng X, Shu-nong L (2003) Purification and adipogenic differentia ...

© Springer International Publishing AG 2017 245 A. Birbrair (ed.), Stem Cell Microenvironments and Beyond, Advances in Experimen ...

246 13.1 Introduction The stem cell microenvironment (niche) plays a major role in controlling the cellu- lar fate and therefore ...

247 cardiac progenitor (neurospheres and cardiospheres, respectively) also showed improved features compared to monolayer cultur ...

248 cellular adhesion molecules, and the addition of exogenous material (see (Gentile 2016 )). Aging of cells represent an addit ...

249 et al. 2016 ), 3D bioprinting of monolayer cells at high density scaffold- free (“bio- printed heart on a chip” (Lind et al. ...

250 acid) [p(NIPAAm-co-AAc] and crosslinked with a peptide (Li et al. 2006 ). These are two examples of 2D and 3D polymeric scaf ...

251 13.2.2.2 Surface Stiffness It is well established that the stiffness of the polymeric construct has a direct and strong infl ...

252 the stiffness of the material and the type of stem cell under investigation. A study by Chowdhury et al. ( 2010 ) demonstrat ...

253 13.2.3 Physico-Chemical Approaches to Engineer the Niche for Stem Cell Differentiation One of the main objectives of using p ...

254 they are being explored as platforms to induce electric stimulation for electrore- sponsive cells such as neurons (Ghasemi-M ...