Esophageal Adenocarcinoma Methods and Protocols
53 considered negative since the primary end point of improving the overall survival was not met (12.2 months versus 10.5 months ...
54 TDM-1 2.4 mg/m^2 was selected by the independent data moni- toring committee after stage one of the study and further com- pa ...
55 America and Latin America appeared to have a survival benefit with the addition of bevacizumab (11.5 months v 6.8 months, HR ...
56 The mTOR belongs to the PI3K-related kinase family and is frequently activated in gastric cancer. It is responsible for regul ...
57 capecitabine) showed improved progression-free survival (median = 4.8 months versus 7.9 months; hazard ratio = 0.47, 95% CI = ...
58 agents targeting at the HCF/MET pathway have no role in the management of metastatic gastric or esophagogastric junction aden ...
59 One hundred and sixty patients were given nivolumab alone or two other different schedules of nivolumab plus ipilimumab, an a ...
60 Regular cardiac assessment for those treated with trastuzumab: echocardiogram or MUGA scan. Monitoring of blood pressure and ...
Table 1 Major phase III clinical studies of target therapy in gastric and esophagogastric junction adenocarcinoma (see Notes 3 a ...
Study Phase N Experimental arm Control arm OS HR OS Exp OS CON OS ab. diff PFS HR PFS Exp PFS CON PFS ab. diff Subgroup: Chinese ...
63 Trastuzumab, ramucirumab, apatinib, and nivolumab are the only target therapies that have proven statistical; if not really, ...
64 gastro-esophageal junction adenocarcinoma (GATSBY): an international randomised, open- label, adaptive, phase 2/3 study. Lanc ...
65 Mariani M, McHugh M, Petrillo M et al (2014) HGF/c-Met axis drives cancer aggres- siveness in the neo-adjuvant setting of ov ...
67 Alfred K. Lam (ed.), Esophageal Adenocarcinoma: Methods and Protocols, Methods in Molecular Biology, vol. 1756, https://doi.o ...
68 there is no universal accepted criterion to identify clearly the esophagogastric junction. It is important to confirm the pat ...
69 Hematoxylin and eosin stained sections after the blocking of specimen. Light microscope. 3 Methods World Health Organizatio ...
70 Dysplasia is a neoplastic stage of the epithelium in which there is the presence of cytological as well as architectural atyp ...
71 Fig. 2 (a) Microscopic appearance showing esophageal stratified squamous epi- thelium (horizontal arrow on right side), gastr ...
72 (C) Mucoepidermoid carcinoma and adenosquamous carcinoma Esophageal mucoepidermoid carcinoma and adenosqua- mous carcinoma ha ...
73 1 or grade 2) adenocarcinoma is less subjective and easier than between grade 1 and grade 2. (B) According to Laurĕn classifi ...
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