Cannabinoids
Structural Requirements for Cannabinoid Receptor Probes 237 References Abadji V, Lin S, Taha G, Griffin G, Stevenson LA, Pertwee ...
238 G.A. Thakur et al. Charalambous A, Yan G, Houston DB, Howlett AC, Compton DR, Martin BR, Makriyannis A (1992) 5′-Azido-∆8-TH ...
Structural Requirements for Cannabinoid Receptor Probes 239 Dutta AK, Ryan W, Thomas BF, Singer M, Compton DR, Martin BR, Razdan ...
240 G.A. Thakur et al. HanusL,BreuerA,TchilibonS,ShiloahS,GoldenbergD,HorowitzM,PertweeRG,Ross RA, Mechoulam R, Fride E (1999) H ...
Structural Requirements for Cannabinoid Receptor Probes 241 by AM1241 inhibits experimental neuropathic pain: pain inhibition by ...
242 G.A. Thakur et al. Lee CM, Zaugg HE, Michaels RJ, Dren AT, Plotnikoff NP, Young PR (1983) New azacannabi- noids highly activ ...
Structural Requirements for Cannabinoid Receptor Probes 243 Mechoulam R, Feigenbaum JJ, Lander N, Segal M, Jarbe TU, Hiltunen AJ ...
244 G.A. Thakur et al. Papahatjis DP, Kourouli T, Abadji V, Goutopoulos A, Makriyannis A (1998) Pharmacophoric requirements for ...
Structural Requirements for Cannabinoid Receptor Probes 245 Rinaldi-Carmona M, Barth F, Heaulme M, Shire D, Calandra B, Congy C, ...
246 G.A. Thakur et al. Thomas BF, Gilliam AF, Burch DF, Roche MJ, Seltzman HH (1998) Comparative recep- tor binding analyses of ...
HEP (2005) 168:247–281 ©cSpringer-Verlag 2005 Cannabinoid Receptors and Their Ligands: Ligand–Ligand and Ligand–Receptor Modelin ...
248 P.H. Reggio An extensive amount of structure–activity relationship information (SAR) has been developed for agonists and ant ...
Cannabinoid Receptors and Their Ligands: Ligand–Ligand and Ligand–Receptor Modeling Approaches 249 Fig. 1.A helix net representa ...
250 P.H. Reggio 1.1 Cannabinoid Receptor Agonists The CB 1 receptor transduces signals in response to CNS-active constituents of ...
Cannabinoid Receptors and Their Ligands: Ligand–Ligand and Ligand–Receptor Modeling Approaches 251 fatty-acid ethanolamides. The ...
252 P.H. Reggio (1997) reported that CHO cells transfected with human CB 1 receptor exhibit high constitutive activity at the le ...
Cannabinoid Receptors and Their Ligands: Ligand–Ligand and Ligand–Receptor Modeling Approaches 253 biological activities and the ...
254 P.H. Reggio 3 Classical/Non-classical CB Pharmacophores Prior to the discovery of the cannabinoid CB 1 receptor,CBSARswerede ...
Cannabinoid Receptors and Their Ligands: Ligand–Ligand and Ligand–Receptor Modeling Approaches 255 indicated that the protons of ...
256 P.H. Reggio stereochemical requirements of the side chain, Busch-Petersen (1996) synthesized a series ofβ-11-hydroxyhexahydr ...
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