Cannabinoids

708 A.H. Lichtman and B.R. Martin Table 1.Potential pharmacotherapies to treat marijuana dependence Drug/class Positive effects ...

Cannabinoid Tolerance and Dependence 709 inhibitor significantly reduced marijuana use as well as depression and alcohol consump ...

710 A.H. Lichtman and B.R. Martin approach examining molecular and cellular changes in conjunction with animal models of depende ...

Cannabinoid Tolerance and Dependence 711 Burkey TH, Quock RM, Consroe P, Roeske WR, Yamamura HI (1997)∆9-TetraHydro- Cannabinoli ...

712 A.H. Lichtman and B.R. Martin DSM-IV (1994) Diagnostic and statistical manual of mental disorders: DSM-IV. American Psychiat ...

Cannabinoid Tolerance and Dependence 713 Gossop M (1988) Clonidine and the treatment of the opiate withdrawal syndrome. Drug Alc ...

714 A.H. Lichtman and B.R. Martin Kouznetsova M, Kelley B, Shen M, Thayer SA (2002) Desensitization of cannabinoid- mediated pre ...

Cannabinoid Tolerance and Dependence 715 Navarro M, Chowen J, Carrera MRA, del Arco I, Vallanua MA, Martin Y, Roberts AJ, Koob G ...

716 A.H. Lichtman and B.R. Martin Rueda D, Galve-Roperh I, Haro A, Guzman M (2000) The CB(1) cannabinoid receptor is coupled to ...

Cannabinoid Tolerance and Dependence 717 Whitlow CT, Freedland CS, Porrino LJ (2003) Functional consequences of the repeated adm ...

HEP (2005) 168:719–756 ©cSpringer-Verlag 2005 Human Studies of Cannabinoids and Medicinal Cannabis P. Robson Department of Psych ...

720 P. R o b s o n humankind. Pioneering clinical research in the last quarter of the twentieth cen- tury has given some support ...

Human Studies of Cannabinoids and Medicinal Cannabis 721 sufferers in 1913, its popularity was in steep decline for a number of ...

722 P. R o b s o n some baseless myths that survive to the present day, culminated in the Marihuana Tax Act (1937) that effectiv ...

Human Studies of Cannabinoids and Medicinal Cannabis 723 tial of cannabis-based medicines among scientists and politicians in a ...

724 P. R o b s o n When I smoke it, my body completely relaxes, which relieves the tension and spasms I have. It has had other b ...

Human Studies of Cannabinoids and Medicinal Cannabis 725 a double-blind, placebo-controlled crossover trial Hanigan et al. (1985 ...

726 P. R o b s o n tion of THC and CBD, or matched placebo at doses determined by titration against symptomrelieforunwantedeffec ...

Human Studies of Cannabinoids and Medicinal Cannabis 727 mented that the primary outcome measure does not correlate with functio ...

728 P. R o b s o n sessed using subjective measures. However, overall, we believe that this study, combined with others which de ...