Synthetic Biology Parts, Devices and Applications
2.5 Complementing Technologies 27 2.5 Complementing Technologies 2.5.1 MAGE The TRMR and T^2 RMR approach of targeting all genes ...
28 2 Trackable Multiplex Recombineering (TRMR) and Next-Generation Genome Design Technologies mechanism, such as E. coli). Howev ...
References 29 References 1 Bailey, J.E. (1991) Toward a science of metabolic engineering. Science, 252 (5013), 1668–1675. 2 Step ...
30 2 Trackable Multiplex Recombineering (TRMR) and Next-Generation Genome Design Technologies 18 Karakousis, G., Ye, N., Li, Z. ...
References 31 34 Garst, A.D., Bassalo, M.C., Pines, G. et al. (2016) Genome-wide mapping of mutations at single-nucleotide resol ...
33 Synthetic Biology: Parts, Devices and Applications, First Edition. Edited by Christina Smolke. © 2018 Wiley-VCH Verlag GmbH & ...
34 3 Site-Directed Genome Modification with Engineered Zinc Finger Proteins use of engineered ZFPs called zinc finger nucleases ...
3.1 ntroduction to Zinc Finger DNA--inding Domains and Cellular epair Mechanisms 35 proven to be very useful for the genomic ma ...
36 3 Site-Directed Genome Modification with Engineered Zinc Finger Proteins 3.2 Approaches for Engineering or Acquiring Zinc Fin ...
3.2 Approaches for Engineering or Accuiring Zinc Finger Proteins 37 3.2.1 Modular Assembly Modular assembly for engineering ZFPs ...
38 3 Site-Directed Genome Modification with Engineered Zinc Finger Proteins tools for evaluating for ZFN target sites within a g ...
3.3 Genome Modification with Zinc Finger Nucleases 39 two sites to introduce two DSBs that may result in a large deletion or chr ...
40 3 Site-Directed Genome Modification with Engineered Zinc Finger Proteins DNA Fok 1 Fok 1 PCR amplification of targeted site H ...
3.6 Zinc Finger Fusions to Transposases and ecombinases 41 The Surveyor nuclease can be used to evaluate if the desired modific ...
42 3 Site-Directed Genome Modification with Engineered Zinc Finger Proteins cell death, and the requirement for cell division ar ...
eferences 43 much research, will tell which genome engineering platform will be most fruitful for desired applications or therap ...
44 3 Site-Directed Genome Modification with Engineered Zinc Finger Proteins 17 Bibikova, M., Carroll, D., Segal, D.J., Trautman, ...
eferences 45 35 Miller, J.C., Holmes, M.C., Wang, J., Guschin, D.Y. et al. (2007) An improved zinc-finger nuclease architecture ...
46 3 Site-Directed Genome Modification with Engineered Zinc Finger Proteins 51 Lee, H.J., Kim, E., and Kim, J.S. (2010) Targeted ...
eferences 47 67 Torikai, H., Reik, A., Soldner, F., Warren, E.H. et al. (2013) Toward eliminating HLA class I expression to gene ...
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